Results: 126

VEGF gene rs35569394 polymorphism in patients with Polycystic Ovary Syndrome

SUMMARY OBJECTIVE: The relationship between the clinicopathological and sociodemographics characteristics of acral melanomas diagnosed at BACKGROUND: This study aimed to investigate the frequency of VEGF gene insertion (I) / deletion (D) polymorphism (rs35569394) in patients with Polycystic Ovarian Synd...

Association between NDO-LID and PGL-1 for leprosy and class I and II human leukocyte antigen alleles in an indigenous community in Southwest Amazon

Braz. j. infect. dis; 24 (4), 2020
The frequencies of the Human leukocyte antigen (HLA) alleles in the Puyanawa indigenous reserve population and their association with the NDO-LID and ELISA PGL-1 rapid serological test was assessed. This was a cross-sectional study with an epidemiological clinical design conducted in two indigenous commu...

Genetic diversity among wild pomegranate (Punica granatum) in Azad Jammu and Kashmir region of Pakistan

BACKGROUND: Pomegranate (Punica granatum L.), one of the most important tropical fruits in Azad Jammu and Kashmir regions of Pakistan, is highly valued for its nutrition and medicinal purposes. Although pomegranate is native to this region, the genetic diversity among wild pomegranate accessions is curre...

Development and application of two novel functional molecular markers of BADH2 in rice

BACKGROUND: Fragrance is one of the most important quality traits in rice, and the phenotype is attributed to the loss-of-function betaine aldehyde dehydrogenase (BADH2) gene. At least 12 allelic variations of BADH2 have been identified, and some of these have been applied to rice fragrance breeding usin...

Molecular analysis of the CYP21A2 gene in dried blood spot samples

Medicina (B.Aires); 80 (3), 2020
Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder due to a deficiency of enzymes involved in cortisol biosynthesis. In more than 90% of cases, CAH is secondary to deleterious mutations in the CYP21A2 gene leading to 21-hydroxilase deficiency (21OHD). The CYP21A2 gene is located on t...

Associação entre diabéticos e câncer intestinal com o risco de mutação no gene CD38 na população iraniana

Arq. gastroenterol; 57 (2), 2020
ABSTRACT BACKGROUND: Intestinal cancer often occurs in type 2 diabetic patients. The concept of increasing insulin levels and insulin-like growth factor in the blood with type 2 diabetes are stimulated with the growth and depletion of cloned cell walls, and the continuation of this process leads to the...

Polimorfismos IL1B-511 y TNF-A-308 en una población infectada con Helicobacter pylori de una zona de bajo riesgo de cáncer gástrico en Nariño-Colombia

Infectio; 24 (2), 2020
Objetivo: Estudiar los polimorfismos IL1B-511 y TNF-A-308 asociaciados a lesiones precursoras de cáncer gástrico (CG) en una población infectada con Helicobacter pylori (H. pylori) de bajo riesgo de CG de Nariño. Material y método: De 105 pacientes con síntomas de dispepsia se incluyeron 81 infe...

Prevalencia del antígeno D débil y su clasificación fenotípica en donantes voluntarios de sangre

En el campo de la medicina transfusional la correcta identificación de los fenotipos del sistema Rh y en especial del antígeno D debe ser de manera inequívoca por su relevancia clínica. El antígeno D tiene variantes denominadas D parcial, D débil y DEL, las que se producen por mutaciones de los ale...

Association between Periodontitis, Genetic Polymorphisms and Presence of Coronary Artery Disease in Southern Brazil

Arq. bras. cardiol; 114 (2), 2020
Abstract Background: Periodontitis and coronary artery disease (CAD) share an inflammatory etiology; there is a recent concern regarding the investigation of an association between these two conditions. Current theories indicate that cytokines and proteins have an important role in this process. C-react...