Results: 114

Personalized approach to growth hormone replacement in adults

ABSTRACT Growth hormone (GH) deficiency (GHD) in adults is well-characterized and includes abnormal body composition, reduced bone mass, an adverse cardiovascular risk profile, and impaired quality of life. In the early 1990s, it was also shown that patients with hypopituitarism without GH replacement th...

Genetic approach in amyotrophic lateral sclerosis

Gac. méd. Méx; 155 (5), 2019
The superoxide dismutase type 1 (SOD1) gene is the first responsible gene mapped in amyotrophic lateral sclerosis type 1 (ALS1), and it codes for the enzyme SOD1, the function of which is to protect against damage mediated by free radicals deriving from oxygen. Its pathophysiological mechanism in ALS1 is...

Vascular endothelial growth factor and pulmonary hypertension in children with beta thalassemia major

J. pediatr. (Rio J.); 95 (5), 2019
Abstract Objective: The purpose of this study was to illustrate the association between vascular endothelial growth factor level and pulmonary artery hypertension in children with β-thalassemia major. Method: This case-control study was conducted on 116 children with β-thalassemia major; 58 o...

Youth homicide: a study of homicide predictor factors in adolescent offenders in custody in the south of Brazil

Abstract Objectives To assess the sociodemographic, psychiatric and criminal profile of adolescent offenders complying with temporary custody for homicide/homicide attempt and to compare it to that of the population of adolescents in custody for other crimes. Methods This cross-sectional study was ba...

Prevalencia de caries temprana de la infancia en el ámbito hospitalario de la Ciudad Autónoma de Buenos Aires

Rev. Círc. Argent. Odontol; 78 (228), 2019
Introducción: La caries dental es una de las enfermedades infecciosas más comunes que afectan a los niños y la afección bucal más prevalente a nivel mundial. En niños preescolares, la caries dental puede presentarse con distintos niveles de severidad, desde la lesión incipiente de mancha blanca ha...

Employment status of people diagnosed with multiple sclerosis in Brazil

Arq. neuropsiquiatr; 77 (5), 2019
ABSTRACT Objective: To describe the employment status of Brazilians with multiple sclerosis (MS). Methods: Analysis of a cross-sectional online survey including questions on demographic and occupational status at the time of diagnosis and survey completion, and time from the first symptom to diagnosis....

Experimentation with tobacco during adolescence as a factor influencing treatment of smoking in adulthood. A retrospective cohort

Säo Paulo med. j; 137 (3), 2019
ABSTRACT BACKGROUND: There are still few studies on predictors of smoking cessation in Brazilian samples. Experimentation with tobacco during adolescence (ETA) may be one of the important predictors. OBJECTIVE: This study aimed, within the context of a treatment-seeking group of subjects, to test the...

Evaluación de la dependencia física y psicológica al tabaco en fumadores mexicanos adultos, Encodat 2016

Salud pública Méx; 61 (2), 2019
Resumen: Objetivo: Evaluar la dependencia física y psicológica de los fumadores mexicanos y su asociación con factores físicos, psicológicos y sociales. Material y métodos: A partir de la Encuesta Nacional de Consumo de Drogas, Alcohol y Tabaco 2016 (n=7 331), se analizó la escala de dependenc...

The prevalence of bruxism and related factors in patients with multiple sclerosis: a comparative study

Arq. neuropsiquiatr; 77 (3), 2019
ABSTRACT Objective: To determine the prevalence of bruxism and related factors in patients with multiple sclerosis (MS). Methods: Diagnosed with relapsing-remitting MS under the 2010-revised McDonald diagnostic criteria, 182 patients without MS exacerbations during the previous three months were includ...

Baseline disease characteristics in Brazilian patients enrolled in Transthyretin Amyloidosis Outcome Survey (THAOS)

Arq. neuropsiquiatr; 77 (2), 2019
ABSTRACT Transthyretin amyloidosis (ATTR) is characterized by the deposit of mutant or wild-type transthyretin that forms amyloid fibrils, which are extracellularly deposited within tissues and organs. Clinical manifestations of familial amyloid polyneuropathy vary according to the mutation, age at onset...