Results: 64

Uso de biomarcadores sanguíneos no diagnóstico da doença de Alzheimer: um futuro próximo?

RBAC. (Online); 51 (4), 2019
A doença de Alzheimer (DA) é uma das formas mais comuns de demência, sendo ela uma patologia neurodegenerativa que acomete pessoas idosas de maneira irreversível. O diagnóstico precoce possibilitaria a realização de tratamentos que apresentassem melhores resultados sobre a redução da severidade ...

A cerebrospinal fluid biosignature for the diagnosis of Alzheimer's disease

Decreased plasmatic spermidine and increased spermine in mild cognitive impairment and Alzheimer's disease patients

Abstract Background Current evidence suggests that upregulation of polyamines system plays a role both in cognitive deficit and synaptic loss observed in Alzheimer's disease (AD). Objective The aim of this study was to determine the plasmatic concentration of polyamines in mild cognitive impairment (...

Canabinoides como uma nova opção terapêutica nas doenças de Parkinson e de Alzheimer: uma revisão de literatura

Rev. bras. neurol; 55 (2), 2019
Os derivados canabinoides podem ser vistos como novos potenciais terapêuticos para o tratamento da doença de Parkinson e Alzheimer. Assim, esta revisão teve como objetivo descrever os efeitos terapêuticos e adversos do uso de canabidiol e de delta-9-tetrahidrocanabinol nas doenças de Parkinson e de ...

Cost-effectiveness analysis of the treatment of mild and moderate Alzheimer's disease in Brazil

Objective: To perform a cost-effectiveness analysis of donepezil and rivastigmine therapy for mild and moderate Alzheimer's disease (AD) from the perspective of the Brazilian Unified Health System. Method: A hypothetical cohort of 1,000 individuals of both sexes, aged >65 years, and diagnosed with AD...

Cirugía neurológica en meningioma del tercio medio del ala del esfenoides. Presentación de un caso

Rev. medica electron; 41 (2), 2019
RESUMEN Se presentó un caso de una paciente de 70 años de edad, con antecedentes patológicos personales de hipertensión arterial controlada, además de un síndrome demencial instaurado hace 5 años aproximadamente. Con un diagnóstico presuntivo de una demencia tipo Alzheimer y sin estudios desde el...

Screening for Alzheimer's disease in low-educated or illiterate older adults in Brazil: a systematic review

Arq. neuropsiquiatr; 77 (4), 2019
ABSTRACT Cognitive screening instruments are influenced by education and/or culture. In Brazil, as illiteracy and low education rates are high, it is necessary to identify the screening tools with the highest diagnostic accuracy for Alzheimer's disease (AD). Objective: To identify the cognitive screenin...

Tasas corregidas de mortalidad atribuible a la demencia por la enfermedad de Alzheimer, Brasil, 2009-2013

Este artículo proporciona estimaciones de las tasas de mortalidad por la demencia por la enfermedad de Alzheimer (DA) en población adulta mayor. Para ello, se usaron datos del Censo Demográfico de 2010 del Instituto Brasileño de Geografía y Estadística (IBGE) y microdatos de mortalidad de las 27 ca...

Accuracy of praxis test from Cambridge Cognitive Examination (CAMCOG) for Alzheimer's disease: a cross-sectional study

Säo Paulo med. j; 136 (5), 2018
ABSTRACT BACKGROUND: Praxis impairment may be one of the first symptoms manifested in dementia, primarily in cortical dementia. The Cambridge Cognitive Examination (CAMCOG) evaluates praxis, but little is known about the accuracy of CAMCOG for diagnosing dementia. The aims here were to investigate the ...

Validity and reliability of the Brazilian Portuguese version of the Australian National University - Alzheimer's Disease Risk Index (ANU-ADRI)

Dement. neuropsychol; 12 (3), 2018
ABSTRACT: The ANU-ADRI is a self-report tool that assesses risk for Alzheimer’s Disease (AD). Objective: To validate an adapted Portuguese version of this instrument and to carry out the reliability Test-Retest of the ANU-ADRI in Brazil. Methods: In this longitudinal study, the sample was formed (n=100...