Abstract:
The aim of this study was to evaluate the functional interaction of
Glycyrrhiza glabra
root
extract (GGRE) on the large conductance Ca
2+
-
activated K
+
(BKCa) channels expressed in the peripheral
nervo
us system by using nociception and inflammation models in rodents
in vivo
....
Glycyrrhiza/química,
Neuralgia/tratamiento farmacológico,
Extractos Vegetales/administración & dosificación,
Nocicepción/efectos de los fármacos,
Subunidades alfa de los Canales de Potasio de Gran Conductancia Activados por Calcio/efectos de los fármacos,
Ratas Wistar,
Extractos Vegetales/farmacología,
Extractos Vegetales/química,
Fenoles/análisis,
Análisis de Varianza,
Raíces de Plantas,
Inflamación,
Modelos Animales
Introduction. Cyclophosphamide (CP) is used to treat malignant neoplasias and control autoimmune diseases. Still, one of its metabolites, acrolein, is toxic to the urothelium and can lead to hemorrhagic cystitis and severe discomfort. Objective.To evaluate the ability of red propolis to prevent and treat...
INTRODUCTION: Rheumatoid arthritis (RA) is classified as an autoimmune, chronic disease affecting diarthrodial joints and periarticular structures. OBJECTIVE: To evaluate whether low-intensity laser treatment (LLLT) and/or exercise reduce the deleterious effects of tissue in a rheumatoid arthritis model....
Abstract Objective Several animal models have been used in fracture healing and bone graft studies, but hematological responses are seldom reported. Therefore, the present study reported the hematological changes observed in rabbits that underwent xenografting of caprine demineralized bone matrix (CDBM)...
Introdução: As limitações das terapias atuais para doenças degenerativas da articulação temporomandibular (ATM) levaram ao aumento do interesse em estratégias regenerativas. A engenharia de tecidos (ET), combinando células-tronco, arcabouços e fatores de crescimento, pode fornecer uma substitui...
We were carried out to investigate the efficacy of Rape (Rapeseed, Brassica napus L.) flower on BPH (benign prostatic hyperplasia) in rats. We found that the extract from Rape flower prevented hyperplasia in testosterone-induced BPH model, the relevant animal model of human BPH. Extract reduced the weigh...
ABSTRACT Purpose: To describe an innovative animal model of eye transplantation used in rabbits. Methods: six Dutch-belted male rabbits were submitted to lateral orbitotomy in the right eye, wide retrobulbar anatomy exposure, dissection of the structures, identification and distal section of the optic ...
Conejos,
Modelos Animales,
Ojo/trasplante,
Nervio Óptico/cirugía,
Electrorretinografía,
Retina/fisiología,
Enucleación del Ojo,
Células Ganglionares de la Retina/fisiología,
Anastomosis Quirúrgica,
Microscopía con Lámpara de Hendidura,
Órbita/cirugía
Nordihydroguaiaretic acid (NDGA) is a natural product obtained by the alkaline extraction of dried plants of Larrea tridentata species. Due to the biological properties presented, such as antioxidant, anti-inflammatory, antiviral and cytotoxic capacity, this compound is being increasingly studied. In thi...
Masoprocol/análisis,
Fenómenos Químicos,
Antioxidantes/farmacología,
Antivirales/farmacología,
Hipoglucemiantes/farmacología,
Modelos Animales,
Neoplasias,
Plantas/clasificación,
Productos Biológicos/análisis,
Toxicidad,
Técnicas In Vitro/métodos
La periodontitis es una patología inflamatoria que aumenta la resorción de hueso alveolar (HA), pérdida de la inserción dentaria y posible exfoliación. Evaluamos el efecto de la administración intermitente de bajas dosis de parathormona (PTH) 1-34 sobre la recuperación de la mas...
SUMMARY: Adipose tissue morphology of different fat tissue depots can be described using the number of adipocytes and cell surface of adipocytes. This study deals with characteristics and morphometric analysis of white and brown adipose tissue depots in healthy adult laboratory mice, hamsters and rats of...
