Results: 59

Evaluation of redox profiles in exogenous subclinical hyperthyroidism at two different levels of TSH suppression

ABSTRACT Objective: Evaluate the relationship between exogenous subclinical hyperthyroidism and oxidative stress through the analysis of the redox profile of patients with subclinical hyperthyroidism exogenous (SCH) grade I (TSH = 0.1 to 0.4 IU/mL) and grade II (TSH < 0.1 IU/mL). Subjects and method...

Trp64Arg polymorphism of the ADRB3 gene associated with maximal fat oxidation and LDL-C levels in non-obese adolescents

J. pediatr. (Rio J.); 94 (4), 2018
Abstract Objective: To analyze the association between the Trp64Arg polymorphism of the ADRB3 gene, maximal fat oxidation rates and the lipid profile levels in non-obese adolescents. Methods: 72 schoolchildren, of both genders, aged between 11 and 17 years, participated in the study. The anthropometric...

A long-term estrogen deficiency in ovariectomized mice is associated with disturbances in fatty acid oxidation and oxidative stress

Abstract Objective The aim of this work was to evaluate the changes caused by estrogen deficiency in lipid metabolism. Methods This study encompassed direct measurements of plasma biochemical analyses, liver lipid contents, and assessments of the mitochondrial β-oxidation capacity as well as an ...

Effect of ozone oxidative preconditioning on inflammation and oxidative stress injury in rat model of renal transplantation

Acta cir. bras; 33 (3), 2018
Abstract Purpose: To investigate the effect of ozone oxidative preconditioning (OzoneOP) on inflammation and oxidative stress injury in rat model of renal transplantation. Methods: Thirty six male Sprague Dawley (SD) rats were randomly divided into three groups. Sham group: rats were treated with open...

Expresión y distribución de las Tioredoxinas durante asfixia perinatal. Su rol en la regulación del equilibrio redox
EXPRESSION AND DISTRIBUTION OF THIOREDOXINS IN PERINATAL ASPHYXIA

Prensa méd. argent; 104 (1), 2018
This article deals with the expression and distribution of Thioredoxins during perinatal asphyxia, and its roll in the regulation of the redox system. Disorders in the gaseous interchange through the placenta and the fetal lungs, can lead to what is known as the perinatal asphyxia (PA). The PA can involv...

Estresse oxidativo como mecanismo comum a várias doenças vasculares: uma análise crítica

Estresse oxidativo é um conceito em evolução. Muito mais do que um simples desbalanço entre oxidantes e antioxidantes, representa um desequilíbrio de vias de sinalização celular redox. Sinalização redox envolve a produção de espécies reativas de oxigênio, radicalares e não radicalares, assi...

Factors that influence the redox state in children: An exploratory study

Clinics; 73 (), 2018
OBJECTIVE: The aim of the present study was to investigate the association of the redox state via malondialdehyde (MDA) as a lipid peroxidation biomarker and hydrophilic antioxidant capacity (HAC) with dietary, anthropometric, demographic, socio-economic and clinical variables as well as the serum concen...

Redox-triggered events in lipid biology: thiol modification and lipidome alteration in ALS

Lipids encompass a wide range of hydrophobic molecules present in cells. The molecular characteristics of lipids determine their cellular localization and biological function. In general, lipids are regarded as essential components of membranes, as energy reservoir and modulators of signaling pathways li...

The long and successful journey of electrochemically active amino acids. From fundamental adsorption studies to potential surface engineering tools

An. acad. bras. ciênc; 90 (1,supl.1), 2018
ABSTRACT Proteins have been the subject of electrochemical studies. It is possible to apply electrochemical techniques to obtain information about their structure due to the presence of five electroactive amino acids that can be oriented to the outside of the peptidic chain. These amino acids are L-Trypt...

Mentha pulegium crude extracts induce thiol oxidation and potentiate hemolysis when associated to t-butyl hydroperoxide in human's erythrocytes

An. acad. bras. ciênc; 89 (4), 2017
ABSTRACT Mentha pulegium (Lamiaceae) tea has been used as a traditional medicine; however, the modulatory effect of M. pulegium extracts on damage to human erythrocytes associated to t-butyl hydroperoxide (t-BHP) exposure remains to be investigated. Accordingly, we perform this study in order to test the...