Abstract Objectives: To determine the prevalence of congenital hypothyroidism in children with filter-paper blood-spot TSH (b-TSH) between 5 and 10 µIU/mL in the neonatal screening. Methods: This was a retrospective study including children screened from 2003 to 2010, with b-TSH levels between 5 and 1...
ABSTRACT Objectives To describe the findings of thyroid ultrasonography (T-US), its contribution to diagnose congenital hypothyroidism (CH) and the best time to perform it. Subjects and methods Forty-four patients with CH were invited to undergo T-US and 41 accepted. Age ranged from 2 months to 45 ye...
É a doença tireoidiana mais comum, com prevalência de 2% na população geral e 15% em pessoas com mais de 60 anos. A doença acomete oito vezes mais mulheres do que homens. A principal forma de apresentação do hipotireoidismo (95% dos casos) é decorrente à alterações primárias na glândula tir...
Dilated cardiomyopathy is usually not reversible. In a few cases diverse etiologies can be treated and cardiomyopathy may disappear or improve significantly. The case of a young man with hypothyroidism and dilated cardiomyopathy is presented. After thyroid hormone replacement, a severe left ventricular d...
ABSTRACT Objective To compare the effects of a unique fixed combination levothyroxine/liothyronine (LT4/LT3) therapy in patients with primary hypothyroidism. Subjects and methods This is a randomized, double-blind, crossover study. Adults with primary hypothyroidism (n = 32, age 42.6 ± 13.3, 30 fema...
Glucemia/análisis,
Peso Corporal/efectos de los fármacos,
Colesterol/sangre,
Estudios Cruzados,
Método Doble Ciego,
Combinación de Medicamentos,
Hipotiroidismo/sangre,
Hipotiroidismo/tratamiento farmacológico,
Calidad de Vida,
Pruebas de Función de la Tiroides,
Tirotropina/efectos de los fármacos,
Tiroxina/sangre,
Tiroxina/farmacología,
Tiroxina/uso terapéutico,
Triyodotironina/sangre,
Triyodotironina/farmacología,
Triyodotironina/uso terapéutico
Campanha, Fábio V G;
Perone, Denise;
Campos, Dijon H S de;
Luvizotto, Renata de A M;
De Síbio, Maria T;
Oliveira, Miriane de;
Olimpio, Regiane M C;
Moretto, Fernanda C F;
Padovani, Carlos R;
Mazeto, Gláucia M F S;
Cicogna, Antonio C;
Nogueira, Célia R.
ABSTRACT Objective The current study was aimed at analyzing sarcoplasmic reticulum Ca2+ ATPase (Serca2) and ryanodine receptor type 2 (Ryr2) gene expression in rats subjected to surgery that induced HF and were subsequently treated with T4 using physiological doses. Materials and methods HF was induc...
Estenosis de la Válvula Aórtica/complicaciones,
Síndromes del Eutiroideo Enfermo/complicaciones,
Síndromes del Eutiroideo Enfermo/tratamiento farmacológico,
Síndromes del Eutiroideo Enfermo/genética,
Expresión Génica/efectos de los fármacos,
Insuficiencia Cardíaca/complicaciones,
Modelos Animales,
ARN Mensajero/metabolismo,
Ratas Wistar,
Canal Liberador de Calcio Receptor de Rianodina/efectos de los fármacos,
Canal Liberador de Calcio Receptor de Rianodina/genética,
ATPasas Transportadoras de Calcio del Retículo Sarcoplásmico/efectos de los fármacos,
ATPasas Transportadoras de Calcio del Retículo Sarcoplásmico/genética,
Tiroxina/administración & dosificación,
Tiroxina/uso terapéutico,
Triyodotironina/efectos de los fármacos
SUMMARY Resistance to thyroid hormone (RTH) coexisting with ectopic thyroid is rare. Here we report a case of RTH with ectopic thyroid. A ten-year-old girl had been misdiagnosed as congenital hypothyroidism and treated with levothyroxine since she was born. Ten-year follow-up showed that the elevated thy...
Hipotiroidismo Congénito/diagnóstico,
ADN/aislamiento & purificación,
Análisis Mutacional de ADN,
Errores Diagnósticos,
Estudios de Seguimiento,
Receptores de Hormona Tiroidea/genética,
Disgenesias Tiroideas/complicaciones,
Disgenesias Tiroideas/diagnóstico por imagen,
Disgenesias Tiroideas/genética,
Síndrome de Resistencia a Hormonas Tiroideas/complicaciones,
Síndrome de Resistencia a Hormonas Tiroideas/genética,
Tirotropina/análisis,
Tiroxina/uso terapéutico,
Factores de Tiempo,
Enfermedades de la Lengua/diagnóstico por imagen
INTRODUCCIÓN: Antecedentes: El presente dictamen expone la evaluación de tecnología del uso de la tirotropina alfa o tirotropina recombinante humana (rhTSH, por su nombre en inglés) como preparación para realizar un rastreo corporal total (RCT) con radioyodo. Esta evaluación específica para pacien...
Although hypothyroidism is associated with an increased prevalence of psychiatric manifestations, myxedema madness is rarely observed. We report the case of a 62-year-old woman with no prior history of psychiatric disorders, who presented to the emergency department with psychomotor agitation 6 weeks aft...
