Introduction: Oral cancer ranks fifth among the most frequent malignant tumors in men
in Brazil. The incidence of this tumor among women has grown. It is still controversial
whether gender can influence the outcome or the prognostic features of the disease.
Objectives: To compare the histopathological fe...
The purpose of this study was to retrospectively review the pathologic complete response (pCR) rate from patients (n=86) with stage II and III HER2-positive breast cancer treated with neoadjuvant chemotherapy at our institution from 2008 to 2013 and to determine possible predictive and prognostic factors...
Antineoplásicos/administración & dosificación,
Biomarcadores de Tumor/sangre,
Neoplasias de la Mama/tratamiento farmacológico,
Neoplasias de la Mama/cirugía,
Quimioterapia Adyuvante/métodos,
Inmunohistoquímica,
Estimación de Kaplan-Meier,
Antígeno Ki-67/sangre,
Mastectomía,
Estadificación de Neoplasias,
Pronóstico,
Receptor ErbB-2/sangre,
Receptores de Estrógenos/sangre,
Receptores de Progesterona/sangre,
Estudios Retrospectivos,
Trastuzumab/administración & dosificación
ABSTRACT OBJECTIVE Analyze the probability of specific survival and factors associated with the risk of death of patients with prostate cancer who received outpatient cancer treatment in the Brazilian Unified Health System, Brazil. METHODS Retrospective cohort study using the National Database of Onc...
Programas Nacionales de Salud/estadística & datos numéricos,
Neoplasias de la Próstata/mortalidad,
Neoplasias de la Próstata/terapia,
Distribución por Edad,
Brasil/epidemiología,
Causas de Muerte,
Hospitalización,
Estimación de Kaplan-Meier,
Estadificación de Neoplasias,
Neoplasias de la Próstata/patología,
Estudios Retrospectivos,
Medición de Riesgo/métodos,
Factores de Riesgo,
Factores de Tiempo,
Resultado del Tratamiento
Abstract The aim of this study was to identify the expression of Ki-67 and MCM3 in oral squamous cell carcinoma (OSCC) as well as to address the correlation with patient survival and clinical features. Samples were collected from 51 patients with OSCC who presented for follow-up. Immunohistochemical expr...
Factores de Edad,
Biopsia,
Carcinoma de Células Escamosas/metabolismo,
Carcinoma de Células Escamosas/mortalidad,
Carcinoma de Células Escamosas/patología,
Inmunohistoquímica,
Estimación de Kaplan-Meier,
Antígeno Ki-67/análisis,
Antígeno Ki-67/metabolismo,
Metástasis Linfática,
Persona de Mediana Edad,
Componente 3 del Complejo de Mantenimiento de Minicromosoma/metabolismo,
Neoplasias de la Boca/metabolismo,
Neoplasias de la Boca/mortalidad,
Neoplasias de la Boca/patología,
Proteínas de Neoplasias/metabolismo,
Estadificación de Neoplasias,
Adhesión en Parafina,
Valores de Referencia,
Factores Sexuales,
Factores de Tiempo,
Carga Tumoral
Abstract: The aim of this study was to evaluate the health-related quality of life (QOL) of patients with squamous cell carcinoma (SCC) according to tumor location. The sample consisted of 27 patients with primary SCC in the oral cavity (n = 15), pharynx (n = 7), and larynx (n = 5) who were undergoing ca...
Factores de Edad,
Análisis de Varianza,
Antineoplásicos/uso terapéutico,
Carcinoma de Células Escamosas/tratamiento farmacológico,
Carcinoma de Células Escamosas/patología,
Estudios Transversales,
Neoplasias Laríngeas/tratamiento farmacológico,
Neoplasias Laríngeas/patología,
Persona de Mediana Edad,
Neoplasias de la Boca/tratamiento farmacológico,
Neoplasias de la Boca/patología,
Estadificación de Neoplasias,
Neoplasias Faríngeas/tratamiento farmacológico,
Neoplasias Faríngeas/patología,
Calidad de Vida,
Factores Sexuales,
Encuestas y Cuestionarios
Detection and treatment of gastric cancer (GC) in early stages is the most effective approach for improving
prognosis. Patients with early gastric cancer (EGC), defined as a type of cancer affecting only mucosa
and submucosa, has a good prognosis in the long-term, and if some criteria are met, endoscopic...
Objetivos: Revisão do processo diagnóstico, estadiamento, conduta terapêutica e seguimento do paciente com câncer (CA) de estômago.
Métodos: selecionados artigos relevantes dos últimos 5 anos sobre a terapêutica do CA gástrico.
Resultados: Sintomas e achados no exame físico do paciente com CA d...
Background: The association of obesity with endometrial cancer is supported by the presence of endoplasmic reticulum (ER) stress in the adipocyte. Glucose-regulated protein 78 (GRP78) is a marker for ER stress. This protein is a central regulator of ER stress due to its major anti-apoptotic role. It play...
ABSTRACT Introduction: The presence and extension of inguinal lymph node metastasis are the main prognostic factors in patients with penile cancer. Physical exam and image exams are not adequate to evaluate inguinal lymph nodes and many patients are submitted to non-therapeutic lymphadenectomies. Howeve...
Brasil/epidemiología,
Carcinoma de Células Escamosas/mortalidad,
Carcinoma de Células Escamosas/patología,
Estudios de Seguimiento,
Ganglios Linfáticos/patología,
Metástasis Linfática,
Persona de Mediana Edad,
Clasificación del Tumor,
Estadificación de Neoplasias,
Neoplasias del Pene/mortalidad,
Neoplasias del Pene/patología,
Pronóstico,
Factores de Riesgo
ABSTRACT Introduction/Background: Fuhrman nuclear grade is the most important histological parameter to predict prognosis in a patient of renal cell carcinoma (RCC). However, it suffers from inter-observer and intra-observer variation giving rise to need of a parameter that not only correlates with nucl...
Carcinoma de Células Renales/patología,
Proliferación Celular,
Inmunohistoquímica,
Antígeno Ki-67/análisis,
Neoplasias Renales/patología,
Persona de Mediana Edad,
Componente 2 del Complejo de Mantenimiento de Minicromosoma/química,
Clasificación del Tumor,
Estadificación de Neoplasias,
Variaciones Dependientes del Observador,
Antígeno Nuclear de Célula en Proliferación/química
