ABSTRACT Objective To prospectively evaluate the perioperative safety, early complications and satisfaction of patients who underwent the implantation of central catheters peripherally inserted via basilic vein. Methods Thirty-five consecutive patients with active oncologic disease requiring chemothe...
Antineoplásicos/administración & dosificación,
Cateterismo Periférico/efectos adversos,
Catéteres de Permanencia/efectos adversos,
Neoplasias/tratamiento farmacológico,
Satisfacción del Paciente,
Complicaciones Posoperatorias,
Calidad de Vida,
Brazo/irrigación sanguínea,
Estudios de Factibilidad,
Complicaciones Intraoperatorias,
Estudios Prospectivos,
Encuestas y Cuestionarios
Abstract Light chain deposition disease (LCDD) is a rare clinical entity characterized by the deposition of light chain immunoglobulins in different tissues and primarily affects the kidneys, followed by the liver and heart. This disease often manifests as nephrotic syndrome with marked proteinuria and r...
Abstract BACKGROUND: Dermatoscopy is a non-invasive diagnostic tool used to examine skin lesions with an optical magnification. It has been suggested as a useful tool for monitoring therapeutic response in lentigo maligna patients treated with imiquimod. OBJECTIVE: To examine the accuracy of dermatosco...
Aminoquinolinas/uso terapéutico,
Antineoplásicos/uso terapéutico,
Carcinoma Basocelular/diagnóstico por imagen,
Carcinoma Basocelular/tratamiento farmacológico,
Dermoscopía/métodos,
Neoplasias Cutáneas/diagnóstico por imagen,
Carcinoma Basocelular/patología,
Trastornos de la Pigmentación/diagnóstico por imagen,
Trastornos de la Pigmentación/tratamiento farmacológico,
Trastornos de la Pigmentación/patología,
Estudios Prospectivos,
Reproducibilidad de los Resultados,
Piel/patología,
Neoplasias Cutáneas/patología,
Factores de Tiempo,
Resultado del Tratamiento
Abstract Objective: To characterize the hearing loss after cancer treatment, according to the type of treatment, with identification of predictive factors. Methods: Two hundred patients who had cancer in childhood were prospectively evaluated. The mean age at diagnosis was 6 years, and at the audiometr...
Factores de Edad,
Antineoplásicos/efectos adversos,
Audiometría de Tonos Puros,
Cisplatino/efectos adversos,
Terapia Combinada,
Pérdida Auditiva Bilateral/diagnóstico,
Pérdida Auditiva Bilateral/etiología,
Pérdida Auditiva Sensorineural/diagnóstico,
Pérdida Auditiva Sensorineural/etiología,
Neoplasias/tratamiento farmacológico,
Neoplasias/radioterapia,
Neoplasias/terapia,
Estudios Prospectivos,
Radioterapia/efectos adversos,
Factores de Riesgo
SUMMARY Introduction The successful development of chemotherapy enabled a fertilitysparing treatment for patients with trophoblastic neoplasia. After disease remission, the outcome of a subsequent pregnancy becomes a great concern for these women. Objective To analyze existing studies in the literature...
Cutaneous melanoma is a highly aggressive tumor developing from melanocytes, its incidence is increasing, and prognosis in advanced stages is daunting. New therapies have been approved during the recent years with unprecedented results, including inhibitors of MAPK/ERK pathway and immune checkpoint block...
Antineoplásicos/uso terapéutico,
Melanoma/tratamiento farmacológico,
Melanoma/secundario,
Neoplasias Cutáneas/tratamiento farmacológico,
Neoplasias Cutáneas/patología,
Antineoplásicos/farmacología,
Protocolos de Quimioterapia Combinada Antineoplásica,
Melanoma/genética,
Quinasas de Proteína Quinasa Activadas por Mitógenos/antagonistas & inhibidores,
Terapia Molecular Dirigida,
Proteínas Proto-Oncogénicas B-raf/antagonistas & inhibidores,
Neoplasias Cutáneas/genética
La eritrodisestesia, o síndrome mano pie, es una reacción adversa relacionada con algunos agentes quimioterápicos. Se caracteriza por comenzar con un pródromo de disestesia palmo-plantar y, entre 2 a 4 días, la sensación progresa a un dolor quemante con edema y eritema en placas bien delimitadas y ...
Summary Objective: To analyze the health care costs specifically related to cardiovascular diseases, which were spent by patients of a private healthcare provider in southern Brazil, after their diagnosis of cancer. Method: We developed an observational, cross-sectional, retrospective study, with a qua...
Antineoplásicos/efectos adversos,
Brasil/epidemiología,
Cardiotoxicidad/diagnóstico,
Enfermedades Cardiovasculares/diagnóstico,
Enfermedades Cardiovasculares/economía,
Enfermedades Cardiovasculares/prevención & control,
Estudios Transversales,
Agencias Gubernamentales,
Gastos en Salud/estadística & datos numéricos,
Hospitalización/economía,
Persona de Mediana Edad,
Neoplasias/tratamiento farmacológico,
Neoplasias/epidemiología,
Neoplasias/terapia,
Sector Privado/economía,
Estudios Retrospectivos,
Sobrevivientes/estadística & datos numéricos
ABSTRACT The present study describes the histopathological and molecular effects of P-MAPA (Protein aggregate magnesium-ammonium phospholinoleate-palmitoleate anhydride) intravesical immunotherapy combined with systemic doxorubicin or cisplatin for treatment of non-muscle invasive bladder cancer (NMIBC) ...
Administración Intravesical,
Antineoplásicos/uso terapéutico,
Vacuna BCG,
Western Blotting,
Carcinoma/patología,
Carcinoma/terapia,
Cisplatino/uso terapéutico,
Terapia Combinada,
Progresión de la Enfermedad,
Doxorrubicina/uso terapéutico,
Inmunoterapia/métodos,
Proteínas de la Membrana/uso terapéutico,
Modelos Animales,
FN-kappa B/análisis,
Fosfohidrolasa PTEN/análisis,
Fosfatidilinositol 3-Quinasas/análisis,
Proteínas Proto-Oncogénicas c-akt/análisis,
Ratas Endogámicas F344,
Reproducibilidad de los Resultados,
Resultado del Tratamiento,
Neoplasias de la Vejiga Urinaria/patología,
Neoplasias de la Vejiga Urinaria/terapia,
Factor A de Crecimiento Endotelial Vascular/análisis
Abstract: Sézary syndrome is a primary cutaneous T-cell lymphoma characterized by the triad of erythroderma, lymphadenopathy and circulating atypical cells. The emergence of new molecular targets has enabled the development of drugs such as alemtuzumab, an anti-CD52 monoclonal antibody, which has shown ...
