Paula, Roberta S;
Souza, Vinícius C;
Machado-Silva, Wilcelly;
Almeida, Bruno Ratier S;
Daros, Andersen C;
Gomes, Lucy;
Ferreira, Aparecido P;
Brito, Ciro J;
Córdova, Cláudio;
Moraes, Clayton F;
Nóbrega, Otávio T.
OBJECTIVES: The number of deaths from vascular diseases is incredibly high worldwide, and reliable markers for major events are still needed. The current cross-sectional study investigated the association of Klotho haplotypes and Klotho serum levels with classic risk factors and a clinical history of vas...
Factores de Edad,
Análisis de Varianza,
Antropometría,
Biomarcadores/sangre,
Proteína C-Reactiva/análisis,
Enfermedad de la Arteria Coronaria/sangre,
Enfermedad de la Arteria Coronaria/genética,
Estudios Transversales,
Ingestión de Energía,
Ensayo de Inmunoadsorción Enzimática,
Técnicas de Genotipaje,
Glucuronidasa/sangre,
Glucuronidasa/genética,
Haplotipos,
Homocisteína/sangre,
Infarto del Miocardio/sangre,
Infarto del Miocardio/genética,
Evaluación Nutricional,
Valores de Referencia,
Factores de Riesgo,
Factores Sexuales,
Estadísticas no Paramétricas,
Accidente Cerebrovascular/sangre,
Accidente Cerebrovascular/genética
ABSTRACT Objective Our aim was to describe the distribution of selected biomarkers according to age and sex, adjusted for HOMA-IR and adiposity, in a subset of middle-aged individuals of Brazilian Longitudinal Study of Adult Health-ELSA without diabetes mellitus or CVD. Subjects and methods This cros...
Adiposidad,
Factores de Edad,
Apolipoproteínas B/sangre,
Aterosclerosis/sangre,
Biomarcadores/sangre,
Brasil,
Estudios Transversales,
Selectina E/sangre,
Resistencia a la Insulina,
Leptina/sangre,
Factores Sexuales,
Circunferencia de la Cintura
Abstract Objective: Childhood obesity has been associated with metabolic syndrome and cardiovascular diseases. This study aimed to compare plasma levels of traditional metabolic markers, adipokines and soluble tumor necrosis factor receptor type 1 (sTNFR1) in overweight, obese and lean children. We also...
Adipoquinas/sangre,
Biomarcadores/sangre,
Glucemia/análisis,
Índice de Masa Corporal,
LDL-Colesterol/sangre,
Estudios Transversales,
Ayuno/sangre,
Resistencia a la Insulina,
Sobrepeso/sangre,
Obesidad Infantil/sangre,
Receptores Tipo I de Factores de Necrosis Tumoral/sangre,
Triglicéridos/sangre
ABSTRACT Objective: To characterize the inflammatory profiles of patients with systemic lupus erythematosus receiving standard treatment compared to healthy controls. Patients and methods: Peripheral venous blood was collected from systemic lupus erythematosus patients (n = 14) and controls (n = 18) at...
Abstract Introduction: Peritonsillar abscess is a serious infectious disease of the tonsillar tissue. Treatment generally requires both medical and surgical approaches to relieve the symptoms. Recently, in addition to clinical follow-up, some inflammatory markers, such as the mean platelet volume and ne...
Objective: Exposure and response prevention (ERP) is effective to treat obsessive-compulsive disorder (OCD), but the lack of tolerance to the aversion nature of exposure techniques results in a high drop-out rate. There have been reports of a generic stress endurance effect of serotonin (5-HT) in the cen...
Terapia Aversiva,
Biomarcadores/sangre,
Plaquetas/química,
Terapia Cognitivo-Conductual/métodos,
Depresión/diagnóstico,
Depresión/terapia,
Estudios de Seguimiento,
Trastorno Obsesivo Compulsivo/sangre,
Trastorno Obsesivo Compulsivo/psicología,
Trastorno Obsesivo Compulsivo/terapia,
Escalas de Valoración Psiquiátrica,
Serotonina/sangre,
Agonistas de Receptores de Serotonina/sangre,
Índice de Severidad de la Enfermedad,
Resultado del Tratamiento
Salas, Carlos;
Cristi-Montero, Carlos;
Fan, Yu;
Durán, Eliana;
Labraña, Ana María;
Martínez, María Adela;
Leiva, Ana María;
Alvarez, Cristian;
Aguilar-Farías, Nicolás;
Ramírez-Campillo, Rodrigo;
Martínez, Ximena Díaz;
Sanzana-Inzunza, Ruth;
Celis-Morales, Carlos.
Background: Sedentary behavior is a major risk factor for cardiovascular disease and mortality. Aim: To investigate whether the associations between sedentary behavior and cardiometabolic markers differs across physical activity levels. Materials and Methods: Cross sectional study of 314 participants age...
Ejercicio Físico/fisiología,
Obesidad/sangre,
Conducta Sedentaria,
Biomarcadores/sangre,
Presión Sanguínea,
Índice de Masa Corporal,
Proteína C-Reactiva/análisis,
Enfermedades Cardiovasculares/etiología,
Enfermedades Cardiovasculares/metabolismo,
Colesterol/sangre,
Estudios Transversales,
Escolaridad,
Índice Glucémico,
Obesidad/fisiopatología,
Valores de Referencia,
Factores de Riesgo,
Factores Sexuales,
Estadísticas no Paramétricas,
Factores de Tiempo,
Triglicéridos/sangre,
Circunferencia de la Cintura
Abstract Objective: To evaluate the validity of clinical and laboratory signs to serious dengue disease in hospitalized children. Methods: Retrospective cohort of children (<18 years) hospitalized with dengue diagnosis (2007-2008). Serious dengue disease was defined as death or use of advanced life ...
Biomarcadores/sangre,
Dengue/sangre,
Dengue/complicaciones,
Dengue/diagnóstico,
Hematócrito,
Hospitalización,
Hipoalbuminemia/sangre,
Hipoalbuminemia/etiología,
Letargia/etiología,
Derrame Pleural/etiología,
Estudios Retrospectivos,
Sensibilidad y Especificidad,
Dengue Grave/sangre,
Dengue Grave/complicaciones,
Dengue Grave/diagnóstico,
Evaluación de Síntomas,
Trombocitopenia/etiología
ABSTRACT Objective To evaluate the usefulness of a third-generation PTH assay in the diagnosis of primary hyperparathyroidism (PHPT). Subjects and methods Forty-one PHPT patients (4 men and 37 women) with 61.2 ± 10.9 (mean ± SD) years, were studied and had PTH levels measured with two different met...
Biomarcadores/sangre,
Brasil,
Estudios de Casos y Controles,
Hiperparatiroidismo Primario/sangre,
Hiperparatiroidismo Primario/diagnóstico,
Inmunoensayo/métodos,
Mediciones Luminiscentes/métodos,
Hormona Paratiroidea/sangre,
Fragmentos de Péptidos/sangre,
Estándares de Referencia,
Valores de Referencia,
Reproducibilidad de los Resultados,
Estadísticas no Paramétricas
