Results: 968

Series de Pediatría Garrahan. El niño con problemas respiratorios

La patología respiratoria presenta un gran desafío para las instituciones de salud, por su frecuencia, su complejidad diagnóstica y terapéutica y la carga que representa en costos económicos y vitales. Estos conceptos se extienden a todos los grupos etarios y sus características han ido cambiando a...

Poluição atmosférica e função pulmonar em asmáticos: associação e interação gene-ambiente

Os poluentes do ar induzem o aumento de componentes inflamatórios no pulmão e redução da função pulmonar. A variabilidade na resposta pulmonar à exposição à poluição atmosférica tem sido associada a polimorfismos em genes envolvidos nas respostas inflamatórias e imunológicas à inalação ...

Cat ownership is associated with increased asthma prevalence and dog ownership with decreased spirometry values

Braz. j. med. biol. res; 51 (12), 2018
The association between pet ownership and the development of allergic and respiratory diseases has been the aim of several studies, however, the effects of exposure in adults remain uncertain. The aims of the present study were to investigate the prevalence of asthma and lung function status among dog an...

Chitosan and carboxymethylated derivative nanoparticles as delivery systems for biological products: preparation, characterization, stability and in vitro/in vivo evaluation

Chitosan is a biocompatible and biodegradable mucoadhesive polymer with unique advantages, such as the distinct trait of opening the junctions to allow paracellular transport of antigen and good tolerability. However, the poor solubility of chitosan in neutral or alkalinized media has restricted its appl...

Hipersensibilidad a corticoides y manejo en asma severa. A propósito de un caso

Resumen Las reacciones de hipersensibilidad a corticoides son raras en la población general, se dividen en dos categorías: Inmediatas, típicamente mediadas por Inmunoglobulina E (IgE), donde se incluye la anafilaxia luego de la administración de un fármaco en un corto período. Su prevalencia descri...

Imbalance of γδT17/γδTreg cells in the pathogenesis of allergic asthma induced by ovalbumin

Braz. j. med. biol. res; 51 (9), 2018
We aimed to explore the imbalance between the T helper 17 γδT cells (γδT17) and the regulatory γδT cells (γδTreg) in asthmatic mice. Male Balb/c mice were randomly divided into the normal control group and the asthmatic model group. The asthmatic model group mice w...

Levels of knowledge about asthma of parents of asthmatic children

Einstein (Säo Paulo); 16 (2), 2018
ABSTRACT Objective To evaluate the levels of knowledge about asthma of parents of school children. Methods A cross-sectional study was carried out with parents of children with medical diagnosis of asthma (mild, moderate and severe), followed up at an outpatient referral center for childhood asthma in ...

Vitamin D3 levels and NLRP3 expression in murine models of obese asthma: association with asthma outcomes

Braz. j. med. biol. res; 51 (1), 2018
Vitamin D (25(OH)D3) is an essential nutrient that plays a role in the immune system. Serum 25(OH)D3 is found to be associated with asthma. However, the role of vitamin D in obese asthma remains unclear. Therefore, we investigated the association between vitamin D levels and asthma outcomes in a murine m...

Estimated cost of asthma in outpatient treatment: a real-world study

ABSTRACT OBJECTIVE To estimate the cost of diagnosis and treatment of asthma. METHODS We used the perspective of society. We sequentially included for 12 months, in 2011-2012, 117 individuals over five years of age who were treated for asthma in the Pneumology and Allergy-Immunology Services of the P...

El diagnóstico médico de asma debería ser reevaluado en pacientes sin tratamiento y asintomáticos
Physician-diagnosed asthma should be reassessed in untreated asymptomatic patients