Results: 93

Suprasellar chordoid glioma: a report of two cases

SUMMARY Chordoid glioma (CG) is considered a slow growing glial neoplasm. We report two new cases with endocrinological presentation, management and outcome. Case reports: 1) An 18 year-old female patient was admitted due to headaches, nausea and vomiting and visual abnormalities. She was in amenorrhea. ...

Seguridad y tolerabilidad de la craneotomía vigíl para tumores cerebrales y otras lesiones supratentoriales
Safety and Tolerability of Vigil Craniotomy for Brain Tumors and Other Supratentorial Lesions

Rev. argent. neurocir; 32 (4), 2018
Objetivos: describir la seguridad y tolerabilidad de craneotomía vigíl en la resección de lesiones supratentoriales. Introducción: La craneotomía vigíl es útil para poder remover tumores cercanos, o en áreas elocuentes con seguridad; potencialmente reduce complicaciones, al igual que costos y est...

Importancia del diagnóstico histopatológico en el tratamiento de las lesiones del tronco cerebral en adultos
Relevance of histopathological diagnosis in the treatment of brainstem lesions in adults

Medicina (B.Aires); 78 (5), 2018
Los tumores del tronco cerebral son infrecuentes en la población adulta. Las controversias surgen cuando se considera la necesidad de confirmar el diagnóstico histopatológico en esta área elocuente del cerebro, balanceando los beneficios de obtener un diagnóstico certero y las desventajas de los pro...

Indications of 5-Aminolevulinic Acid and Intraoperative MRI in Glioma Surgery: First Cases in Latin America in a Single Reference Center

Arq. bras. neurocir; 37 (2), 2018
Introduction The improvement on the extent of resection (EOR) of gliomas with the combination of 5-aminolevulinic acid (5-ALA) and intraoperative magnetic resonance imaging (iMRI) has been demonstrated in previous studies. We present our results with the combined use of 5-ALA and (iMRI) in the surgery of...

Genetic variants related to angiogenesis and apoptosis in patients with glioma

Arq. neuropsiquiatr; 76 (6), 2018
ABSTRACT Background Glioma, the most common primary malignant brain tumor in adults, is highly aggressive and associated with a poor prognosis. The objectives of this study were to evaluate the association of genetic polymorphisms related to angiogenesis and apoptosis with gliomas, as well as comorbidi...

Estudio de mutaciones en los genes IDH1 e IDH2 en una muestra de gliomas de población colombiana

Biomédica (Bogotá); 38 (supl.1), 2018
Resumen Introducción. Los gliomas son los tumores primarios más comunes del sistema nervioso central y se clasifican de I a IV según su grado de malignidad. En recientes investigaciones se ha encontrado que su aparición está relacionada con mutaciones en el exón 4 de los genes que codifican las d...

Translatômica aplicada ao descobrimento de alterações moleculares em gliomas

O glioblastoma (GBM) está entre os tipos tumorais mais agressivos e de menor resposta a terapias, o que requer, portanto, uma melhor compreensão sobre o comportamento deste tipo tumoral, auxiliando no desenvolvimento de novos tipos de tratamento para a doença. Atualmente, dados de expressão gênica e...

Papel da Stress Inducible Phosphoprotein One (STI1) e da proteína prion celular na angiogênese tumoral

Proteínas multifuncionais podem ser consideradas uma vantagem evolutiva celular, ao passo que uma única proteína divide-se, simultaneamente, entre suas funções intracelulares e a sinalização extracelular para complementar mecanismos de responsividade tecidual. No papel de co-chaperona, a STI1 se c...

Bioinformatics analysis of microarray data to reveal the pathogenesis of diffuse intrinsic pontine glioma

Biol. Res; 51 (), 2018
BACKGROUND: Diffuse intrinsic pontine glioma (DIPG) is the main cause of pediatric brain tumor death. This study was designed to identify key genes associated with DIPG. METHODS: The gene expression profile GSE50021, which consisted of 35 pediatric DIPG samples and 10 normal brain samples, was downloaded...