Results: 89

Higher values of triglycerides: HDL-cholesterol ratio hallmark disease severity in children and adolescents with sickle cell anemia

Braz. j. med. biol. res; 52 (10), 2019
Dyslipidemia has been described in sickle cell anemia (SCA) but its association with increased disease severity is unknown. Here, we examined 55 children and adolescents with SCA as well as 41 healthy controls to test the association between the lipid profiles in peripheral blood and markers of hemolysis...

Low Levels of High-density Lipoprotein in Patients with Pediatric Cancer at Diagnosis

Rev. bras. cancerol; 65 (3), 2019
Introduction: Cancer patients have metabolic imbalances due to the disease, treatment and their complications. Increases in triglycerides and glucose profile and catabolism of protein have been described and are associated with inflammatory response as result of the tumor activity or necrosis. Objective:...

Prevalência de colesterol total e frações alterados na população adulta brasileira: Pesquisa Nacional de Saúde

Rev. bras. epidemiol. (Online); 22 (supl.2), 2019
RESUMO: Objetivo: Analisar as prevalências dos níveis de colesterol total e frações alterados na população brasileira, segundo dados bioquímicos da Pesquisa Nacional de Saúde. Métodos: Estudo descritivo, utilizando dados laboratoriais da Pesquisa Nacional de Saúde coletados entre os anos de...

Association of alanine aminotransferase concentration with cardiometabolic risk factors in children and adolescents: the CASPIAN-V cross-sectional study

Säo Paulo med. j; 136 (6), 2018
ABSTRACT BACKGROUND: It has been suggested that the levels of some liver enzymes, and especially alanine aminotransferase (ALT), might be correlatable with cardiometabolic risk factors. We investigated the relationship between ALT concentration and cardiometabolic risk factors among children and adoles...

Comparação entre dietas com restrição de carboidratos e de gorduras no combate à obesidade: uma revisão sistemática

OBJETIVO: Comparar dietas com restrição de carboidratos e com restrição de gorduras, para analisar a eficácia de ambas em relação a perda de peso, LDL-c, HDL-c, triglicerídeos, glicemia em jejum e pressão arterial. MÉTODOS: Foram analisados, em três diferentes bancos de dados, estudos de inter...

Is FGF-23 an early indicator of atherosclerosis and cardiac dysfunction in patients with gestational diabetes?

ABSTRACT Objective: Fibroblast growth factor 23 (FGF-23) is a phosphorus-regulating hormone and plays a role in the pathogenesis of myocardial hypertrophy. The aim of this study was to evaluate the association of FGF-23 levels with echocardiographic parameters and insulin resistance (IR) in patients wit...

Influencia del consumo de quinua sobre parámetros bioquímicos e histomorfometría intestinal en ratas obesas

RESUMEN Objetivo . Determinar la influencia del consumo de tres variedades de quinua sobre parámetros bioquímicos e histomorfometría intestinal en ratas obesas. Materiales y Métodos . Se utilizaron 42 ratas obesas Holtzman dispuestas en siete tratamientos de seis animales cada uno, que fueron alime...

Is Lipid Accumulation Product Associated with an Atherogenic Lipoprotein Profile in Brazilian Subjects?

Arq. bras. cardiol; 110 (4), 2018
Abstract Background: Lipid accumulation product (LAP), a simple and low-cost tool, is a novel biomarker of central lipid accumulation and represents a potential surrogate marker for atherogenic lipoprotein profile. However, its association with lipoprotein subfractions has not been described in the lite...

Metabolic syndrome and psoriasis: a study in 97 patients

SUMMARY BACKGROUND: Psoriasis is associated with higher prevalence of metabolic syndrome (MS). The prevalence of MS varies according to the studied population as it suffers influence of genetics, aging, sedentary behaviour and diet. OBJECTIVE: To study the prevalence of MS in local psoriasis patients a...

Assessing cardiovascular risk in ATM heterozygotes

Summary Objective: To evaluate the carotid intima-media complex (CIMC) thickness and lipid metabolism biomarkers associated with cardiovascular risk (CR) in parents of patients with ataxia-telangiectasia and verify an association with gender. Method: A cross-sectional and controlled study with 29 ATM h...