Results: 39

Adult acute lymphoblastic leukemia

Rev. bras. hematol. hemoter; 31 (supl.2), 2009
This review focuses on the most recent advances in the diagnostic and prognostic work-up of adult acute lymphoblastic leukemia (ALL), and on their implications in the clinical management of the disease. Over the years, information obtained through extensive immunophenotyping, karyotyping, molecular genet...

Monitoramento de doença residual mínima em leucemia mielóide crônica por PCR em tempo real: [revisão]
Monitoring minimal residual disease in chronic myeloid leukemia by real time PCR: [review]

O monitoramento de doença residual mínima (DRM) em leucemia mielóide crônica é extremamente importante, pois possibilita o diagnóstico precoce de eventuais recidivas da doença. Este estudo visa apresentar uma revisão bibliográfica sobre a aplicação e a avaliação da eficácia do método de PC...

Margens comprometidas e extensão glandular presentes em peças de conização como fatores preditores de doença residual
Involved margins and glandular extension in conization specimens as predictive factors of residual disease

Femina; 32 (2), 2004
Qualquer que seja o método utilizado para o tratamento das lesões intra-epiteliais cervicais há sempre a possibilidade de ocorrência de lesão residual ou recorrente. Um modo de prever a ocorrência da doença residual ou recorrente se torna de extrema relevância, na medida que durante o manejo pós...

Fluorescent in-situ hybridization (FISH) for BCR/ABL in chronic myeloid leukemia after bone marrow transplantation

Säo Paulo med. j; 119 (1), 2001
CONTEXT: Identification of Philadelphia chromosome or BCR/ABL gene rearrangement in chronic myeloid leukemia is important at diagnosis as well as after treatment. OBJECTIVE: To compare the results of karyotyping using fluorescent in-situ hybridization (FISH) upon diagnosis and 1 year after bone marrow tr...

Detecçäo de doença residual mínima(DRM) em pacientes com leucemia mielóide aguada(LMA), através da técnica de citometria de fluxo multiparamétrica(CFM)

As leucemias mielóides agudas, na sua maioria, recaem no primeiro ano do diagnóstico decorrente da presença da doença residual mínima. A citometria de fluxo multiparamétrica tem sido usada na busca de doença residual, através dos fenótipos aberrantes. Objetivo: Avaliar a presença da doença res...

Seguimiento citogenético e hibridización in situ (FISH) en la enfermedad mínima residual
[Cytogenetic and in situ hybridization (FISH) follow-up in minimal residual disease]

Medicina (B.Aires); 60 Suppl 2 (), 2000
Cytogenetic studies are an important tool for diagnosis, prognosis and minimal residual disease (MRD) follow up specially in oncohematology. Conventional cytogenetics, also known as G banding technique, brings complete information for the spectrum of aneuploidies and structural changes present in maligna...

The detection and significance of minimal residual disease in chronic myeloid leukemia

Medicina (B.Aires); 60 Suppl 2 (), 2000
The focus of the study of minimal residual disease (MRD) is to redefine the concept of remission by using more sensitive molecular techniques to detect level of disease burden below that of conventional pathology. The detection of the chimeric bcr-abl mRNA transcript in chronic myeloid leukemia (CML) is ...

Rol de la colonoscopia en el seguimiento de los pacientes sometidos a una resección curativa por cáncer colorrectal
Colonoscopy role in the follow up of colorectal cancer patients submitted to a resective surgery

Rev. chil. cir; 50 (2), 1998
Los pacientes sometidos a una resección curativa (RC) por cáncer colorrectal (CCR) tienen mayor riesgo de desarrollar una 21 lesión neopiásica. La colonoscopia es un elemento diagnóstico valioso en el seguimiento de estos pacientes. No está claramente establecida la frecuencia con que este examen d...

Endogenous and exogenously-induced immunomodulation of tumour-host responsiveness

Mem. Inst. Oswaldo Cruz; 82 (supl.2), 1987
In spite of the availability of multiple effector mechanisms of the immune system to combat tumour growth and metastases, their impairment frequently accompanies the appearance of cancer. Factors contributing to this impairment may be related to properties of the host and/or the tumour itself and may be ...