La introducción de los moduladores de acidez gástrica como profilaxis contra las úlceras por estrés en pacientes críticos se ha ido convirtiendo en una práctica de rutina tanto en la unidad de cuidados intensivos como fuera de esta; sin embargo, el desco-nocimiento de la fisiopa...
Objective: To analyze the late results of advanced Chagasic megaesophagus treatment by esophagectomy associated with the use of proton pump inhibitor (omeprazole) as for the incidence of esophagitis and Barrett's esophagus in the remaining stump. Methods : We studied patients with advanced megaesophagus ...
Es un benzimidazol sustituido que inhibe, a través de un nuevo mecanismo de acción, la secreción ácida en el estómago mediante su efecto específico sobre la bomba de ácido en las células parietales. Mecanismo de acción: es una base débil que se convierte a su forma activa únicamente en el medi...
Desde 1988, o omeprazol e outros inibidores de bomba de próton (IBP) têm sido prescritos frequentemente e de forma crônica. Seu amplo uso levantou algumas preocupações sobre a segurança do tratamento crônico com IBPs. Desde então vários relatos de casos e trabalhos têm mostrado uma relação ca...
Prevalence of adverse neuropsiquiatric reactions to drugs, in hospitalized patients in the services of clinic, surgery, pediatrics and gynecology-obstetrics of Hospital Vicente Corral 2014
La prevalencia de reacciones adversas a los medicamentos (RAM) de tipo neuropsiquiátricas se encuentra alrededor del 11,4% del total de las reacciones adversas registradas según la mayoría de estudios. En nuestro medio carecemos de datos.Objetivo: Determinar la prevalencia de RAM ...
The main aim of this study was to develop a multiparticulate system containing mini-tablets of omeprazole formulated with an enteric polymer with pH-dependent solubility. Pre-formulation studies showed good flow and compaction capacity, leading to the production ofhigh quality mini-tablets. The mini-tabl...
BACKGROUND: Recent concerns have been raised about the potential for proton pump inhibitors (PPIs) to blunt the efficacy of clopidogrel. We observed the effect of clopidogrel plus aspirin with or without omeprazole in patients with carotid stenoses after they received placement of carotid stents. METHODS...
Randomized comparative study between levofloxacin, omeprazole, nitazoxanide and doxycycline versus triple therapy for the eradication of Helicobacter pylori