Results: 506

Mycobacterium leprae: aspectos da resistência aos fármacos na poliquimioterapia

Introdução: O diagnóstico da hanseníase possui números significativos que causam preocupação à saúde pública. Os casos de resistência medicamentosa nessa doença se iniciaram em meados dos anos 60 e diante do problema, a Organização Mundial da Saúde instituiu em 1981 a poliquimioterapia, as...

Adverse effects of polychemotherapy for leprosy in 13 years of follow-up at a university hospital

An. bras. dermatol; 96 (2), 2021
Abstract Leprosy is one of the neglected diseases in the world and Brazil is the second country with more cases. A retrospective study was conducted based on the medical records of 196 leprosy patients diagnosed during the course of 13 years at a university hospital. The aim was to describe the adverse e...

Cases of leprosy notified in the municipality of Parnaíba, state of Piauí, Brazil, 2007-2016

Acta sci., Health sci; 43 (), 2021
This study aimed to describe the epidemiological and clinical characteristics of leprosy cases reported in the municipality of Parnaíba, State of Piauí. This was a cross-sectional study of leprosy cases, living in Parnaíba, State of Piauí, reported to the National System of Notifiable Di...

Case for diagnosis. Erythematous and infiltrated plaques in the infrahyoid region

An. bras. dermatol; 96 (1), 2021
Abstract Leprosy is a chronic infectious disease caused by Mycobacterium leprae and, depending on the host immune status, presents different clinical forms. This report describes the case of a 46-year-old man who had hypoesthetic lesions in the infrahyoid region for 30 days. The bacilloscopy was negative...

Effectiveness of triple therapy with dapagliflozin add-on to dual therapy over 52 weeks in patients with uncontrolled type 2 diabetes mellitus in a centre of high complexity, Cali-Colombia

ABSTRACT Objectives: To evaluate the effectiveness of adding dapagliflozin as an intensification strategy for the treatment of patients with uncontrolled type 2 diabetes mellitus (T2DM). Materials and methods: A historical cohort study was conducted in 123 adult patients over 18 years old who were diag...

Tratamento farmacológico da estrongiloidíase em pacientes transplantados

O objetivo deste artigo foi comparar o uso da ivermectina e do albendazol em pacientes transplantados e relatar os respectivos sucessos terapêuticos nessa população. Foram analisados artigos que abordassem relatos de casos publicados nos últimos 4 anos no PubMed® relacionando os descritores “trans...

Early liver function improvement following successful treatment of chronic hepatitis C in patients with decompensated cirrhosis: a real-life study

Clinics; 76 (), 2021
OBJECTIVES: Despite higher rates of sustained virologic response (SVR), important concerns remain when patients with decompensated cirrhosis due to hepatitis C virus (HCV) are treated with direct-acting antiviral agents (DAA). Questions include efficacy, safety, and the magnitude of liver function improv...

A real-life study of the positive response to DAA-based therapies for hepatitis C in Brazil

Braz. j. infect. dis; 25 (2), 2021
ABSTRACT A retrospective cohort of 11,308 chronic hepatitis C infected patients treated with regimens that included Sofosbuvir (SOF), Daclatasvir (DCV), Simeprevir (SMV), or an association of Ombitasvir, Veruprevir/Ritonavir and Dasabuvir (3D) with or without Ribavirin (RBV) were assessed for sustained v...

Hydroxychloroquine with azithromycin in patients hospitalized for mild and moderate COVID-19

Braz. j. infect. dis; 25 (2), 2021
ABSTRACT Objectives: To assess the efficacy of hydroxychloroquine in combination with azithromycin in terms of clinical and biochemical outcomes in adult patients with COVID-19 hospitalized for acute respiratory distress syndrome (ARDS), and to describe the occurrence of adverse events. Method: Retrosp...

Perfil de pacientes que concluíram o tratamento poliquimioterápico da hanseníase: um estudo transversal

Ciênc. cuid. saúde; 20 (), 2021
RESUMO Introdução: a hanseníase é uma doença infectocontagiosa que prevalece como problema de saúde pública no Brasil. Objetivo: descrever o perfil sociodemográfico, de tratamento e clínico de pacientes que concluíram o tratamento poliquimioterápico para a hanseníase. Método: estudo trans...