Results: 255

Protective effect of L-carnitine on myocardial injury in rats with heatstroke

Acta cir. bras; 35 (12), 2020
Abstract Purpose: To investigate the protective effect of L-carnitine on myocardial injury in rats with heatstroke. Methods: orty-eight rats were randomly divided into control, heatstroke and 25, 50 and 100 mg/kg L-carnitine groups. The last three groups were treated with 25, 50 and 100 mg/kg L-carniti...

Effect of topical Insulin administration on bone defect healing in diabetic rats

Braz. dent. sci; 23 (2), 2020
Objective: insulin has been reported to possess anabolic effect on bone. Topical application of insulin in bone defects in diabetic rats has not been investigated. The objective of this study was to evaluate histologically the effect of topical administration of insulin for the restoration of tibial bone...

Antioxidant effect of endothelin-1 receptor antagonist protects the rat kidney against chronic injury induced by hypertension and hyperglycemia

J. bras. nefrol; 41 (4), 2019
ABSTRACT Hypertension and Diabetes mellitus are the two main causes of chronic kidney disease that culminate in the final stage of kidney disease. Since these two risk factors are common and can overlap, new approaches to prevent or treat them are needed. Macitentan (MAC) is a new non-selective antagonis...

Estudio histopatológico de tejido cardiaco de roedores infectados con Trypanosoma cruzi capturados en barrios suburbanos de Mérida, México

Biomédica (Bogotá); 39 (supl.2), 2019
Resumen Introducción. Trypanosoma cruzi es el agente causal de la tripanosomiasis americana, enfermedad endémica en México. Los roedores Mus musculus y Rattus rattus son reservorios del parásito, el cual invade las fibras cardiacas y desarrolla nidos parasitarios produciendo diversas lesiones. Los e...

¿El licopeno puede eliminar los efectos perjudiciales de la hiperoxia en los cerebros inmaduros?

Arch. argent. pediatr; 117 (4), 2019
Objetivos: Al ser un antioxidante, el licopeno protege a las células contra el daño causado por los radicales libres, fortalece los enlaces intercelulares y mejora el metabolismo celular. Este estudio analiza los efectos del licopeno sobre los trastornos neurodegenerativos por hiperoxia en ratas recié...

Evaluation of the neurotoxic effects of intrathecal administration of (S)-(+)-Ketoprofen on rat spinal cords: randomized controlled experimental study

Rev. bras. anestesiol; 69 (4), 2019
Abstract Background and objectives Intrathecal administration of non-steroidal anti-inflammatory drugs is more efficacious for post-operative pain management. Cyclooxygenase inhibiting non-steroidal anti-inflammatory drugs like (S)-(+)-Ketoprofen, may be effective at lower intrathecal doses than parente...

Angiostrongylus (Parastrongylus) cantonensis en huéspedes intermediarios y definitivos en Ecuador, 2014-2017

Biomédica (Bogotá); 39 (2), 2019
Resumen Introducción. Angiostrongylus cantonensis es un serio problema de salud pública y está ampliamente distribuido en el país. Cuando el parásito infecta a los caracoles terrestres Achatina, se enquista en su interior y puede infectar accidentalmente a las personas y otros mamíferos. Objetivo...

Curcuma Longa Abolishes Phenylephrine-Induced Contractions in Isolated Aortic Artery of Rats

Curcuma longa has biological effects. Its cardiovascular activities are yet to be scientifically studied. Objectives: To investigate the vasorelaxant effects of the aqueous extract of Curcuma longa (AECL). Methods: Aortic annuli of normotensive rats, with or without endothelium, were set up in a data s...

Bone repair induced by different bone graft substitutes in critical-sized defects in rat calvaria

Abstract Introduction The use of bone substitutes in grafting procedures as an alternative of the use of autogenous bone graft has been indicated, however, the direct comparison between these biomaterials has been little explored. Objective To evaluate the effect of different osteoconductive bone subst...

Evaluation of the biological quality of defatted pequi (Caryocar brasiliense Cambess) seed flour protein supplemented with lysine to rats (Rattus norvegicus)

Rev. Nutr. (Online); 32 (), 2019
ABSTRACT Objective In the biome of the Brazilian Cerrado, there are a lot of fruit tree species that stand out for their sensory quality and for presenting potentialities in the market of pulp and almond. Among these species, the pequi deserves attention because it has an almond rich in proteins and tha...