Results: 1561

Carvedilol as primary prophylaxis for gastric variceal bleeding in portal hypertension model in rats

ABCD (São Paulo, Impr.); 33 (3), 2020
ABSTRACT Background: Portal hypertension (PH) can be measured indirectly through a hepatic vein pressure gradient greater than 5 mmHg. Cirrhosis is the leading cause for PH and can present as complications ascites, hepatic dysfunction, renal dysfunction, and esophagogastric varices, characterizing gast...

Structural bases of gastrointestinal motility changes in parkinson's disease: study in rats

ABCD (São Paulo, Impr.); 33 (3), 2020
ABSTRACT Background: Gastrointestinal disorders are frequently reported in patients with Parkinson's disease whose disorders reduce the absorption of nutrients and drugs, worsening the clinical condition of patients. However, the mechanisms involved in modifying gastrointestinal pathophysiology have not...

Effect of supplementation with probiotics on colonic anastomoses in rats: morphological and tensiometric study

ABCD (São Paulo, Impr.); 33 (4), 2020
ABSTRACT Background: The use of probiotics positively modifies the composition and function of intestinal flora, improving the quality of intestinal anastomosis. Aim: To evaluate the impact of probiotic use on intestinal anastomosis of rats. Method: Thirty-six adult male Wistar rats (Rattus norvegic...

Could the intestinal epithelial alterations promoted by roux-en-y gastric bypass explain higher tendency for colonic diseases in bariatric patients?

ABCD (São Paulo, Impr.); 33 (4), 2020
ABSTRACT Background: Intestinal diversions have revolutionized the treatment of morbid obesity due to its viability and sustained response. However, experimental studies suggest, after these derivations, a higher risk of colon cancer. Aim: To analyze the histological and immunohistological changes that...

Does the association of tacrolimus and mycophenolate mofetil change the healing of the abdominal wall? study in rats submitted to ischemia and kidney reperfusion

ABCD (São Paulo, Impr.); 33 (4), 2020
ABSTRACT Background: Tacrolimus and mycophenolate mofetil are immunosuppressive agents widely used on the postoperative period of the transplants. Aim: To evaluate the influence of the association of them on the abdominal wall healing in rats. Methods: Thirty-six Wistar rats were randomly assigned ...

Estudo comparativo do uso do gel de própolis e da geleia real no tratamento da mucosite oral induzida quimicamente? Estudo experimental in vivo
Comparative study of the use of propolis gel and royal jelly in the treatment of chemically induced oral mucositis? In vivo experimental study

Objetivo: Avaliar os efeitos da própolis(P) e da geleia real(GR) em comparação a terapia de fotobiomodulação (FBM) com laser de baixa intensidadeem um modelo animal de mucosite oral (MO) quimioinduzida por 5-fluorouracil (5-FU). Adicionalmente, verificar por meio de uma revisão sistemática da lite...

Consideraciones Metodológicas en el Estudio Histomorfométrico del Hueso Interradicular de los Primeros Molares Inferiores de Ratas Wistar
Methodological Considerations in the Histomorphometric Study of the Interradicular Bone of the First Lower Molars of Wistar Rats

El objetivo fue evaluar el volumen óseo BV/TV (%) del hueso interradicular en ratas Wistar: A) en relación a la edad; B) en relación a la zona de estudio en animales de la misma edad. Se utilizó Grupo A) 15 ratas Wistar hembras de 6 (I), 10 (II) y 14 (III) semanas, Grupo B) 9 ratas Wistar macho de 8 ...

Glabridin alleviates ischemia/reperfusion-induced functional failure of smooth muscle of rat ileum by upregulating the cAMP

Despite the development of modern medicine, alternative medicine, which has not lost its timeliness, remains attractive for the treatment of various diseases. Glabridin, a major flavonoid of Glycyrrhiza glabra, is known for its antioxidant and anti-inflammatory activity. The aim of this study was: 1) to...

Increased levels of hexacosanoic acid in the brain of Winstar rats: a behavioral study

Clin. biomed. res; 40 (3), 2020
Introduction: X-linked adrenoleukodystrophy (X-ALD) is a peroxisomal metabolic disorder associated with mutations in the ATP-binding cassette sub-family D member1 (ABCD1) gene. Practically all male patients with X-ALD develop adrenocortical insufficiency during childhood and progressive myelopathy and pe...

Ibuprofen increases the serum Omentin levels in rats after abdominal surgery

SUMMARY AIMS Omentin is an adipokine primarily produced by visceral adipose tissue and its reduced levels have been shown to be associate with worse metabolic outcomes. We aimed to study the effects of preoperative ibuprofen on postoperative omentin levels in rats after surgery. METHODS Forty-eight a...