Results: 72

Evaluation of antioxidant therapy in experimental Chagas disease

Abstract INTRODUCTION: Stimulation of inflammatory mediators such as cytokines and chemokines may cause oxidative stress in Chagas disease. In this study, we evaluated the merit of vitamins C and E as antioxidant therapy to minimize the oxidative stress-induced damage in an experimental model of Chagas...

Caracterización y estudio fitoquímico de Justicia secunda valh (Sanguinaria, Singamochilla, Insulina)
Characterization and phytochemical study of Justicia secunda valh (sanguinaria, singamochilla, insulina)

Rev. cuba. plantas med; 22 (1), 2017
Introducción: las hojas de Justicia secunda Vahl. son ampliamente utilizadas en las poblaciones rurales de la costa ecuatoriana. Los pobladores la utilizan con fines medicinales sin que se hayan comprobado las propiedades que se le atribuye. El presente estudio se realizó con los extractos hidroalcohó...

Resveratrol Treatment Normalizes the Endothelial Function and Blood Pressure in Ovariectomized Rats

Arq. bras. cardiol; 108 (2), 2017
Abstract Background: Despite knowing that resveratrol has effects on blood vessels, blood pressure and that phytostrogens can also improve the endothelium-dependent relaxation/vasodilation, there are no reports of reveratrol's direct effect on the endothelial function and blood pressure of animals with ...

Systematic review of recovery of spinal cord injury with antioxidant therapy

Coluna/Columna; 16 (1), 2017
ABSTRACT The objective of the paper is to analyze the frequency and efficacy of experimental studies with antioxidant therapy. A search was conducted in the pubmed.gov database using the keywords "antioxidants" AND "spinal cord injury", from January 2000 to December 2015, resulting in 686 articles. Studi...

Evaluation of basil extract ( Ocimum basilicum L. ) on oxidative, anti-genotoxic and anti-inflammatory effects in human leukocytes cell cultures exposed to challenging agents

ABSTRACT Ocimum is one of the most important genera of the Lamiaceae family. Several studies about basil and its popular use reveal many characteristics of the herb, including its use as antioxidant, anti-aging, anti-inflammatory, anti-carcinogenic, anti-microbial, and cardiovascular agents, among others...

Efecto del extracto purificado rico en antocianinas del fruto del maqui (Aristotelia chilensis) en un modelo experimental de hígado graso no alcohólico

Gastroenterol. latinoam; 28 (4), 2017
Background: Non-alcoholic fatty liver disease (NAFLD) is a spectrum of hepatic lesions, ranging from benign intrahepatic lipid accumulation (steatosis) to progressive non-alcoholic steatohepatitis, in absence of other known secondary causes. Both insulin resistance and oxidative stress have been involved...

Anti-inflammatory effect of lycopene on endotoxin-induced uveitis in rats

Arq. bras. oftalmol; 79 (6), 2016
ABSTRACT Purpose: We evaluated the efficacy of lycopene, a dietary carotenoid and potent antioxidant, against ocular inflammation and oxidative stress in an experimental uveitis model. Methods: Endotoxin-induced uveitis (EIU) was induced in Sprague-Dawley rats by a single subcutaneous injection of 200 ...

Estudio fitoquímico y evaluación de la actividad antioxidante de Esenbeckia litoralis Donn.Sm. (Loro grande)
Phytochemical study and evaluation of the antioxidant activity of Esenbeckia litoralis Donn. Sm. (loro)

Rev. cuba. plantas med; 21 (4), 2016
Introducción: la especie Esenbeckia litoralis Donn.Sm. (Rutaceae) es también conocida como Loro o Loro grande, ha sido empleado en la medicina tradicional para el tratamiento de mordeduras de serpientes, dolor de garganta y lesiones ocasionadas por picaduras de insectos. Esta variedad de actividades so...

Low-dose resveratrol supplementation on heart rate variability in hypertensive volunteers: a controlled double-blind trial

OBJECTIVE: Hypertension decreases the heart rate variability (HRV). Resveratrol, a phenolic compound found in grapes and their products, has been explored for its potential to treat hypertension. We evaluated the effects of low-dose resveratrol on HRV in hypertensive volunteers. METHOD: Twenty-one hyper...

Effect of curcumin on visfatin and zinc-α2-glycoprotein in a rat model of non-alcoholic fatty liver disease

Acta cir. bras; 31 (11), 2016
ABSTRACT PURPOSE: To investigate the effect of curcumin on visfatin and zinc-α2-glycoprotein (ZAG) expression levels in rats with non-alcoholic fatty liver disease (NAFLD). METHODS: Fifty-six male rats were randomly divided into a control group (n=16) and model group (n=40) and were fed on a norm...