Abstract INTRODUCTION: This study investigated the genetic environment of bla KPC-2 in Klebsiella pnemoniae multi-drug resistant clinical isolates. METHODS: Four carbapenemase gene isolates resistant to carbapenems, collected from infected patients from two hospitals in Brazil, were investigated using...
Antibacterianos/farmacología,
ADN Bacteriano/genética,
Farmacorresistencia Bacteriana Múltiple,
Infecciones por Klebsiella/microbiología,
Klebsiella pneumoniae/enzimología,
Klebsiella pneumoniae/genética,
Klebsiella pneumoniae/aislamiento & purificación,
Pruebas de Sensibilidad Microbiana,
Plásmidos/genética,
Reacción en Cadena de la Polimerasa,
beta-Lactamasas/genética
Abstract INTRODUCTION: Carbapenem-resistant Klebsiella pneumoniae infection lacks treatment options and is associated with prolonged hospital stays and high mortality rates. The production of carbapenemases is one of the most important factors responsible for this multi-resistance phenomenon. METHODS: ...
Antibacterianos/farmacología,
Proteínas Bacterianas/genética,
Brasil,
ADN Bacteriano,
Farmacorresistencia Bacteriana Múltiple/genética,
Infecciones por Klebsiella/microbiología,
Klebsiella pneumoniae/efectos de los fármacos,
Klebsiella pneumoniae/genética,
Klebsiella pneumoniae/aislamiento & purificación,
Pruebas de Sensibilidad Microbiana,
Reacción en Cadena de la Polimerasa,
Prevalencia,
beta-Lactamasas/genética
Santana, Monique Freire;
Pivoto, Guilherme;
Alexandre, Márcia A. Araujo;
Baía-da-Silva, Djane Clarys;
Borba, Mayla Gabriela da Silva;
Val, Fernando Almeida;
Brito-Sousa, Jose Diego;
Melo, Gisely Cardoso;
Monteiro, Wuelton Marcelo;
Souza, João Vicente Braga;
Pinheiro, Silviane Bezerra;
Ferreira, Luiz Carlos Lima;
Naveca, Felipe Gomes;
Nascimento, Valdinete Alves;
Corado, André Lima Guerra;
Hajjar, Ludhmila Abrahão;
Silva Neto, João Ricardo;
Siva, George Alan Villarouco;
Pasqualotto, Alessandro C;
Lacerda, Marcus Vinícius Guimarães.
Abstract We present postmortem evidence of invasive pulmonary aspergillosis (IPA) in a patient with severe COVID-19. Autopsies of COVID-19 confirmed cases were performed. The patient died despite antimicrobials, mechanical ventilation, and vasopressor support. Histopathology and peripheral blood galactom...
Aspergillus/genética,
Aspergillus/aislamiento & purificación,
Autopsia,
Betacoronavirus,
Infecciones por Coronavirus,
Infecciones por Coronavirus/complicaciones,
Infecciones por Coronavirus/patología,
Resultado Fatal,
Aspergilosis Pulmonar Invasiva/complicaciones,
Aspergilosis Pulmonar Invasiva/patología,
Pulmón/microbiología,
Pandemias,
Neumonía Viral/complicaciones,
Neumonía Viral/patología
Abstract The differential diagnosis of optic neuritis is broad and varied. We report the case of a 24-year-old Brazilian man who presented with five-week history of fever, malaise, myalgia, severe fatigue, tender right preauricular lymphadenopathy, and acute vision blurring associated with right optic di...
Abstract INTRODUCTION: The diagnostic accuracy of Xpert MTB/RIF (Xpert) in pulmonary tuberculosis (PTB) in children is lower than in adults. In Brazil, the diagnosis of PTB is based on a diagnostic score system (DSS). This study aims to study the role of Xpert in children and adolescents with PTB sympt...
ABSTRACT Objective: Nontuberculous mycobacteria (NTM) are a heterogeneous group of bacteria that are widely distributed in nature and associated with opportunistic infections in humans. The aims of this study were to identify NTM in patients with suspected tuberculosis who presented positive cultures an...
Proteínas Bacterianas/genética,
Técnicas de Tipificación Bacteriana,
Brasil,
Chaperonina 60/genética,
ARN Polimerasas Dirigidas por ADN/genética,
Variación Genética,
Infecciones por Mycobacterium no Tuberculosas/diagnóstico,
Infecciones por Mycobacterium no Tuberculosas/microbiología,
Mycobacterium avium/genética,
Mycobacterium avium/aislamiento & purificación,
Micobacterias no Tuberculosas/aislamiento & purificación
RESUMO Objetivo Avaliar características clínicas, tomográficas e microbiológicas dos pacientes com doença pulmonar causada pela M. kansasii (DPMK) atendidos em unidade ambulatorial no período 2006-2016. Métodos Estudo descritivo, em que foram analisados 38 pacientes. Foram analisadas as caracter...
Antituberculosos/uso terapéutico,
Brasil/epidemiología,
Farmacorresistencia Microbiana,
Etambutol/uso terapéutico,
Isoniazida/uso terapéutico,
Pulmón/diagnóstico por imagen,
Enfermedades Pulmonares/tratamiento farmacológico,
Enfermedades Pulmonares/microbiología,
Infecciones por Mycobacterium no Tuberculosas/diagnóstico,
Infecciones por Mycobacterium no Tuberculosas/tratamiento farmacológico,
Infecciones por Mycobacterium no Tuberculosas/epidemiología,
Mycobacterium kansasii/aislamiento & purificación,
Rifampin/uso terapéutico,
Tomografía Computarizada por Rayos X,
Resultado del Tratamiento
The occurrence of leptospirosis is significantly higher in the tropical climate than in temperate regions, especially in periods with high rainfall levels. In horses, leptospirosis can range from subclinical to asymptomatic but maintains an important role in the transmission of leptospiro...
Salmonellosis is a relevant public health threat worldwide. Reptiles are commonly involved in human cases. A microbiological survey was conducted from August to October 2018 to isolate Salmonella bacteria and de-termine if they were resistant to regularly used antibiotics in eight species of pet turtles ...
La punta morada es una enfermedad que afecta la producción de algunas especies de solanáceas como la papa y el tomate, causando enrollamiento en las puntas de las hojas con una marcada coloración morada, decaimiento temprano de la planta y en la papa se observa tuberización aérea. Como patógenos as...
