Gougerot and Carteaud confluent and reticulated papillomatosis (CARP) is an uncommon dermatosis characterized by hyperpigmented scaly macules or papillomatous papules coalescing into confluent patches or plaques centrally with a reticular pattern peripherally. We report a 28-year-old woman presenting at ...
Abstract: Background: Heparanase is an enzyme that cleaves heparan sulfate chains. Oligosaccharides generated by heparanase induce tumor progression. Basal cell carcinoma and squamous cell carcinoma comprise types of nonmelanoma skin cancer. Objectives: Evaluate the glycosaminoglycans profile and expre...
Carcinoma Basocelular/enzimología,
Carcinoma de Células Escamosas/enzimología,
Glucuronidasa/metabolismo,
Glicosaminoglicanos/metabolismo,
Neoplasias Cutáneas/enzimología,
Párpados/enzimología,
Glucuronidasa/genética,
Glicosaminoglicanos/análisis,
Ácido Hialurónico/análisis,
Ácido Hialurónico/metabolismo,
Queratinocitos/metabolismo,
ARN Mensajero/metabolismo,
Reacción en Cadena en Tiempo Real de la Polimerasa/métodos
Abstract: Sézary syndrome is a primary cutaneous T-cell lymphoma characterized by the triad of erythroderma, lymphadenopathy and circulating atypical cells. The emergence of new molecular targets has enabled the development of drugs such as alemtuzumab, an anti-CD52 monoclonal antibody, which has shown ...
Abstract: Mohs micrographic surgery is a technique used to excise skin tumors based on comprehensive surgical mapping, in which the surgeon removes the tumor, followed by a complete histological evaluation of the tumor's margins. The correlation of the presence of a tumor in histological examinations and...
Carcinoma Basocelular/cirugía,
Carcinoma de Células Escamosas/cirugía,
Cirugía de Mohs/normas,
Recurrencia Local de Neoplasia/cirugía,
Guías de Práctica Clínica como Asunto,
Neoplasias Cutáneas/cirugía,
Carcinoma Basocelular/patología,
Carcinoma de Células Escamosas/patología,
Márgenes de Escisión,
Cirugía de Mohs/métodos,
Neoplasias Cutáneas/patología
Abstract: Blue nevi are benign melanocytic lesions located in the deeper reticular dermis, consequence of failure of melanocytic migration into the dermal-epidermal junction from the neural crest. Lesions are usually asymptomatic and solitary, but may present in a multiple or agminated (grouped) pattern....
Abstract Plasmoacanthoma is an extremely rare verrucous tumor located on periorificial regions characterized by dense dermal plasmacytic infiltrates. Some authors classify it as a form of reactive plasma cell proliferation which represents a heterogeneous spectrum of mucocutaneous disorders. These plasma...
Abstract Verrucous epidermal nevi are hamartomatous lesions of the epidermis that, unlike other epidermal nevi (such as sebaceous nevus or nevus comedonicus), are rarely associated with malignant neoplasms. The majority of squamous cell carcinoma develop in linear or multiple epidermal nevus and rarely i...
Carcinoma de Células Escamosas/etiología,
Nevo Sebáceo de Jadassohn/complicaciones,
Neoplasias Cutáneas/etiología,
Biopsia,
Carcinoma de Células Escamosas/patología,
Epidermis/patología,
Neoplasias Primarias Múltiples/complicaciones,
Neoplasias Primarias Múltiples/patología,
Nevo Sebáceo de Jadassohn/patología,
Neoplasias Cutáneas/patología,
Úlcera Cutánea/patología
Abstract Oculoectodermal syndrome is a rare disease characterized by the association of aplasia cutis congenita, epibulbar dermoids, and other abnormalities. This report describes the twentieth case of the disease. We report a 4-year-old female child who presented with the classical features of the syndr...
Abstract The occurrence of multiple primary melanomas in a single individual is rare. Most commonly, malignant melanocytic lesions subsequent to the initial diagnosis of melanoma are secondary cutaneous metastases. We report a patient with gastrointestinal bleeding from gastric metastasis of cutaneous me...
Neoplasias Encefálicas/secundario,
Melanoma/secundario,
Neoplasias Primarias Múltiples/patología,
Neoplasias Cutáneas/patología,
Neoplasias Gástricas/secundario,
Biopsia,
Neoplasias Encefálicas/genética,
Inhibidor p18 de las Quinasas Dependientes de la Ciclina/genética,
Dermoscopía,
Melanoma/genética,
Mutación,
Neoplasias Primarias Múltiples/genética,
Neoplasias Cutáneas/genética,
Neoplasias Gástricas/genética
