To find the predictors of High Dose Methotrexate toxicities in childhood Acute Lymphoblastic Leukemia Patients. This study included 198 Childhood Acute Lymphoblastic Leukemia patients (303 infusions) who were treated with High Dose Methotrexate. Methotrexate levels at different time point were measured b...
Ethnomedicinal survey documents the traditional practices of Tetrastigma angustifolia leaves in the management of diabetes in the North-eastern region of India. The present study was aimed at isolation of possible antidiabetic principle(s) from T. angustifolia leaves and evaluation of antidiabetic effica...
To evaluate the clinical outcomes of daptomycin therapy and adherence to treatment recommendations, a retrospective cohort study was conducted with patients that received daptomycin during the period of the study. The adherence and nonadherence to clinical guidelines were assessed through organism identi...
Ethylenediamine tetraacetic acid (EDTA) is used in various medical applications. The aim of this study is to investigate the antitumor efficacy of EDTA alone or with cisplatin (Cis). Fifty male albino mice were used to assess the median lethal dose (LD50) of EDTA via intraperitoneal (i.p) injection. To d...
Objectives. This study sought to compare the estimated glomerular filtration rate and the indication of dose adjustment of antimicrobials when using Cockcroft-Gault or Modification of Diet in Renal Disease. Methods. A cross-sectional study was performed with patients admitted to the intensive care unit o...
Diacerein is a symptomatic slow-acting drug used for treating osteoarthritis. This drug is completely metabolized into the active metabolite rhein before reaching the systemic circulation. This study evaluated the effects of food on the pharmacokinetics of rhein released from diacerein in healthy Chinese...
Ingestión de Alimentos,
Alimentos/efectos adversos,
Farmacocinética,
Osteoartritis/patología,
Absorción,
Cápsulas/clasificación,
Dosificación/efectos adversos,
Estudios Cruzados,
Pueblo Asiatico/etnología,
Preparaciones Farmacéuticas/análisis,
Programas Informáticos,
Voluntarios Sanos
Abstract Background: Sugammadex has made it possible to reverse any type of rocuronium-induced block quickly and safely. The most frequent neuromuscular blockade is the moderate one where doses smaller than those recommended by the industry could get a full reversal. Objective: We aimed to evaluate the...
Carvajal P, Germán;
Aponte M, Diego;
Ibáñez P, Milcíades;
Castañeda-Orjuela, Carlos;
González S, Carlos;
Preciado A, Javier;
Sánchez L, Carlos;
Rocha R, Nicolas;
Prieto O, Robin;
Reyes M, Gustavo;
Romero G, Juan;
Echeverry A, Diana;
Sabbagh S, Luis.
Resumen Introducción: la colonoscopia es el examen estándar de oro para evaluar la mucosa del colon. De la limpieza del colon en la preparación intestinal para colonoscopia depende el hallazgo de pólipos, que pueden ser adenomatosos con potencial maligno y con la posibilidad de degenerarse en cánce...
Introdução: A vacina de febre amarela, recomendada em áreas endêmicas, é contraindicada em alérgicos à proteína do ovo (APO) por ser cultivada em ovos de galinha embrionados. Objetivo: O objetivo do estudo foi mostrar a segurança da vacina de febre amarela em pacientes comprovadamente APO. Méto...
Desensibilización Inmunológica,
Fiebre Amarilla,
Hipersensibilidad al Huevo,
Vacuna contra la Fiebre Amarilla,
Proteínas del Huevo,
Seguridad,
Pruebas Intradérmicas,
Pacientes,
Inmunoglobulina E,
Estudios Prospectivos,
Dosificación,
Dilución,
Antagonistas de los Receptores Histamínicos,
Anafilaxia
Resumo Objetivo: Verificar a associação entre as interrupções e os erros de medicação nas doses preparadas e administradas por profissionais de enfermagem das unidades de internação de clínica médica de dois hospitais públicos localizados no Distrito Federal, Brasil. Metodologia: Estudo expl...
