Results: 208

Deformação miocárdica (strain) e fibrose miocárdica na forma cardíaca leve da Doença de Chagas

ABC., imagem cardiovasc; 34 (3), 2021
Fundamento: A identificação precoce do dano miocárdico parece ser importante na abordagem do paciente com doença de Chagas. A ecocardiografia com strain obtida por speckle tracking e a avaliação da fibrose miocárdica por meio da ressonância magnética cardíaca podem ser métodos diagnósticos pr...

Comportamento dos critérios de uso apropriado da cintilografia de perfusão miocárdica na avaliação de assintomáticos de alto risco cardiovascular ou com doença coronária conhecida

ABC., imagem cardiovasc; 34 (3), 2021
Fundamentos: O papel da cintilografia de perfusão miocárdica em pacientes assintomáticos permanece restrito a situações clínicas muito específicas, muitas delas abordadas nos Critérios de Uso Apropriado (AUC) de Cintilografia de Perfusão Miocárdica. Objetivo: Realizar uma análise crí...

MicroRNA-302b mitigates renal fibrosis via inhibiting TGF-β/Smad pathway activation

Braz. j. med. biol. res; 54 (3), 2021
Renal fibrosis is one of the most significant pathological changes after ureteral obstruction. Transforming growth factor-β (TGF-β) signaling pathway plays essential roles in kidney fibrosis regulation. The aims of the present study were to investigate effects of microRNA-302b (miR-302b) on ren...

hsa-miR-4443 inhibits myocardial fibroblast proliferation by targeting THBS1 to regulate TGF-β1/α-SMA/collagen signaling in atrial fibrillation

Braz. j. med. biol. res; 54 (4), 2021
Fibrosis caused by the increase in extracellular matrix in cardiac fibroblasts plays an important role in the occurrence and development of atrial fibrillation (AF). The aim of this study was to investigate the role of hsa-miR-4443 in AF, human cardiac fibroblast (HCFB) proliferation, and extracellular m...

External iliac artery endofibrosis in an elite female endurance cyclist

Abstract External iliac artery endofibrosis is a rare pathology that affects high-level endurance athletes, especially cyclists. Classical symptoms include pain, loss of power, and/or cramp in the affected limb while training at maximal effort. The patient's lack of atherosclerotic risk factors makes cli...

Mast cells in the pathophysiology of Duchenne muscular dystrophy in Golden Retriever dogs

Pesqui. vet. bras; 40 (10), 2020
The Golden Retriever muscular dystrophy (GRMD) is one of the best models of Duchenne muscular dystrophy (DMD), with similar genotypic and phenotypic manifestations. Progressive proliferation of connective tissue in the endomysium of the muscle fibers occurs in parallel with the clinical course of the dis...

Electrólisis percutánea intratisular en el tratamiento del dolor
Percutaneous intratissue electrolysis in pain management

Rev. cuba. med. mil; 49 (2), 2020
En los estudios de los últimos años, se ha propuesto el uso de una novedosa terapia denominada electrólisis percutánea intratisular (EPI), para el tratamiento del dolor en diversas enfermedades. La electrólisis percutánea guiada por ultrasonido, implica la transferencia de corriente galvánica dent...

Renal transplant patients with preformed anti-HLA antibodies: early biopsy findings and clinical outcomes

J. bras. nefrol; 42 (2), 2020
Abstract Introduction: Renal fibrosis is the end point of a process that begins at transplant, with ischemia reperfusion and early inflammation, and progresses over time with immunological and non-immunological phenomena. Early identification of morphological markers and intervention could improve graft...

Variable beige adipocyte morphology in obese rats by different times of melatonin administration

Int. j. morphol; 38 (3), 2020
This study aimed to evaluate changes in beige adipocytes at different times of melatonin administration, in the morning (ZT01) or in the evening (ZT11), at 30 mg/kg daily by gavage for 7 weeks or continuously with drinking water in the term of high-calorie diet-induced obesity (HCD). Melatonin received a...

Síndrome metabólico, hígado graso no alcohólico y hepatocarcinoma

Actual. nutr; 21 (2), 2020
En las últimas décadas, los cambios en el estilo de vida pro-vocaron un incremento en la prevalencia del síndrome meta-bólico y que la enfermedad por hígado graso no alcohólico (nonalcoholic fatty liver disease, NAFLD sus siglas en inglés) se convierta en la enfermedad hepática cr...