An old acquaintance with new trends: Systemic lupus erythematosus
Rev. colomb. reumatol; 28 (supl.1), 2021
Results: 410
Osteoporosis and osteonecrosis in systemic lupus erythematosus
Rev. colomb. reumatol; 28 (supl.1), 2021
ABSTRACT Half of the patients with systemic lupus erythematosus (SLE) will have a reduced bone density and more than one in ten will develop osteoporosis (OP) prematurely. Multiple risk factors have been related to loss of bone mass, but just a few are modifiable, such as adequate vitamin D and calcium i...
Systemic lupus erythematosus, a disease conditioned by the environment
Rev. colomb. reumatol; 28 (supl.1), 2021
ABSTRACT Systemic lupus erythematosus is an autoimmune disease that involves several systems, affects mainly young adult women, and causes a significant deterioration in quality of life. Different environmental aspects are known to facilitate the development of lupus in predisposed individuals. For sever...
Accelerated atherosclerosis and cardiovascular disease in systemic lupus erythematosus
Rev. colomb. reumatol; 28 (supl.1), 2021
ABSTRACT Cardiovascular disease (CVD), particularly coronary heart disease and stroke, is one of the most important causes of morbidity and mortality in patients with systemic lupus erythematosus (SLE). The increased prevalence of CVD and subclinical atherosclerosis, even after adjustment for traditional...
Construction of a questionnaire to characterise environmental exposures in patients with systemic lupus erythematosus
Rev. colomb. reumatol; 28 (4), 2021
ABSTRACT Introduction: As the knowledge of systemic lupus erythematosus (SLE) advances, the need to characterise the burden of environmental exposure in patients becomes increasingly relevant. However, there is currently no tool validated to measure such exposure. For this reason, the objective of this...
Agreement between biopsy and renal function in pediatric patients with lupus nephritis. A retrospective study
Rev. colomb. reumatol; 28 (4), 2021
ABSTRACT Introduction: Lupus nephritis (LN) is a consequence of Systemic Lupus Erythematosus (SLE). Renal biopsy is a potential prognostic biomarker for renal function. Objective: To correlate histopathological findings and renal function in children with LN. Materials and methods: A retrospective ...
The heterogeneity of systemic lupus erythematosus: Looking for a molecular answer
Rev. colomb. reumatol; 28 (supl.1), 2021
ABSTRACT The heterogeneity of SLE is a major limitation when designing clinical trials and understand ing the mechanisms of the disease. The analyses conducted before the new technologies for the identification of the single cell transcriptome focused on the detection of molecular patterns such as interf...
Systemic lupus erythematosus and pregnancy: Strategies before, during and after pregnancy to improve outcomes
Rev. colomb. reumatol; 28 (supl.1), 2021
ABSTRACT Systemic lupus erythematosus is a multisystemic autoimmune disorder that predominantly affects women in reproductive years. Pregnancy in women with SLE is still considered a high-risk condition although several strategies may improve maternal and fetal outcomes. Preconception counseling is funda...
Organ damage in systemic lupus erythematosus
Rev. colomb. reumatol; 28 (supl.1), 2021
ABSTRACT Damage reflects the irreversible changes that occur in systemic lupus erythematosus (SLE) patients as a consequence of the disease, its treatment or comorbidities. The pattern of damage increases in a steady linear fashion over time. At least half of all patients with SLE will have some form of ...
Diagnosis and treatment of articular manifestations of systemic lupus erythematosus
Rev. colomb. reumatol; 28 (supl.1), 2021
ABSTRACT Articular involvement in Systemic Lupus Erythematosus (SLE) is well recognized as one of the most common manifestations of the disease. This article reviews the recent knowledge of the clinical manifestations, diagnostic techniques and therapies used for the treatment of joint involvement in SLE...