Abstract The right subclavian artery may originate from the left portion of the aortic arch. This aberrant vessel is known as the arteria lusoria. Its course to its usual site runs behind the esophagus, which may cause a disease known as dysphagia lusoria, responsible for symptoms of discomfort. This art...
Abstract Thoracoabdominal aortic aneurysms (TAAA) present special challenges for repair due to their extent, their distinctive pathology, and the fact that they typically cross the ostia of one or more visceral branch vessels. Historically, the established treatment for TAAA was open surgical repair, wit...
O objetivo deste estudo foi verificar os efeitos da restrição calórica sobre a morfologia da aorta torácica em ratos envelhecidos e, a partir dessa análise, inferir sobre a capacidade dessa intervenção em refrear as alterações histológicas observáveis no transcorrer cronológico. Foram utiliza...
The aorta is the main arterial trunk in the human body, however, its variation was extremely variable. During an educational dissection, aberrant branching pattern of aortic arch was found in a Korean cadaver. The brachiocephalic trunk (innominate artery) originated from the aortic arch at the left side ...
OBJECTIVE: We aimed to determine whether aerobic training decreases superoxide levels, increases nitric oxide levels, and improves endothelium-dependent vasodilation in the aortas of spontaneously hypertensive rats. METHODS: Spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY) were distribu...
Aorta Torácica/fisiopatología,
Western Blotting,
Endotelio Vascular/fisiopatología,
Etidio/análogos & derivados,
Prueba de Esfuerzo,
Fluorescencia,
Hemodinámica,
Hipertensión/fisiopatología,
NAD/análisis,
NG-Nitroarginina Metil Éster/análisis,
NG-Nitroarginina Metil Éster/metabolismo,
Óxido Nítrico Sintasa de Tipo III/análisis,
Óxido Nítrico Sintasa de Tipo III/metabolismo,
Nitritos/análisis,
Nitritos/metabolismo,
Condicionamiento Físico Animal/fisiología,
Distribución Aleatoria,
Ratas Endogámicas SHR,
Valores de Referencia,
Reproducibilidad de los Resultados,
Superóxidos/análisis,
Superóxidos/metabolismo,
Natación/fisiología,
Factores de Tiempo,
Vasodilatación/fisiología
Abstract Background: Physical exercise is an important tool for the improvement of endothelial function. Objective: To assess the effects of acute dynamic resistance exercise on the endothelial function of spontaneously hypertensive rats (SHR). Methods: Ten minutes after exercise, the aorta was remove...
Acetilcolina,
Aorta Torácica/química,
Aorta Torácica/metabolismo,
Aorta Torácica/fisiopatología,
Western Blotting,
Endotelio Vascular/química,
Endotelio Vascular/metabolismo,
Endotelio Vascular/fisiopatología,
Prueba de Esfuerzo,
Hipertensión/metabolismo,
Hipertensión/fisiopatología,
NG-Nitroarginina Metil Éster,
Óxido Nítrico/análisis,
Óxido Nítrico/metabolismo,
Óxido Nítrico Sintasa de Tipo II/metabolismo,
Óxido Nítrico Sintasa de Tipo III/análisis,
Óxido Nítrico Sintasa de Tipo III/metabolismo,
Fenilefrina,
Fosforilación/fisiología,
Condicionamiento Físico Animal/fisiología,
Prostaglandinas/metabolismo,
Factores de Tiempo,
Vasoconstricción/fisiología
Levels of hydrogen sulfide (H2S), a gaseous signaling molecule, are reduced in the serum of individuals who smoke. We hypothesized that tobacco smoke influenced smooth muscle relaxation by decreasing H2S levels and this effect could also influence expression of cystathionine γ-lyase (CSE) and sulfon...
BACKGROUND: Pathologic vascular smooth muscle cell (VSMC) proliferation and migration after vascular injury promotes the development of occlusive vascular disease. Therefore, an effective chemical agent to suppress aberrant proliferation and migration of VSMCs can be a potential therapeutic modality for ...
Movimiento Celular/efectos de los fármacos,
Proliferación Celular/efectos de los fármacos,
Músculo Liso Vascular/efectos de los fármacos,
Miocitos del Músculo Liso/efectos de los fármacos,
Niacinamida/análogos & derivados,
Pirimidinas/farmacología,
Quinasa Syk/antagonistas & inhibidores,
Aorta Torácica/efectos de los fármacos,
Músculo Liso Vascular/citología,
Niacinamida/farmacología,
Cicatrización de Heridas/efectos de los fármacos,
Western Blotting,
Ensayos de Migración Celular,
Células Cultivadas,
Relación Dosis-Respuesta a Droga,
Evaluación Preclínica de Medicamentos,
Ratas Sprague-Dawley,
Reproducibilidad de los Resultados,
Factores de Tiempo