INTRODUCTION: Treatment for multiple sclerosis should focus on relapse prevention and treatment, as well as symptom and disease progression control, which require the use of multiple medications. OBJECTIVE: To evaluate the association of polypharmacy and related clinical, epidemiological factors in multi...
Gonçalves, Marcus Vinícius Magno;
Siquineli, Fábio;
Ribas, Flavio Diniz;
Longo, Alexandre Luiz;
Amaral, Claudio Henrique do;
Chikota, Edila Miers;
Wille, Paulo Roberto;
Eboni, Áudred Cristina Biondo;
Liberato, Rafaela Bittencourt;
Morales, Rogério Rizo;
Becker, Jefferson;
Lana-Peixoto, Marco Aurélio.
ABSTRACT Background: The Brazilian Committee for Treatment and Research in Multiple Sclerosis (BCTRIMS) has launched an initiative to determine the prevalence of multiple sclerosis (MS) in Brazil, based on key cities deemed representative of their regions in terms of demographic and environmental featur...
Tauil, Carlos Bernardo;
Ramari, Cintia;
DA Silva, Flávia Martins;
Brasil, Erica;
David, Ana de;
Gomes, Jaqueline Ramos Andrade;
Silva, Felipe von Glehn;
BrandÃo, Carlos Otávio;
Dos Santos, Leonilda Maria Barbosa;
Santos-Neto, Leopoldo dos.
ABSTRACT Background: Multiple sclerosis (MS) is an immune-mediated disease that affects the central nervous system. The impact of MS transcends physical functions and extends to psychological impairment. Approximately 50% of people with MS develop depressive symptoms during their lifetime and depressiv...
Communication is an essential part of our social participation and the need to know how to evaluate and deal with its alterations is essential when working with people with neurological pathologies such as Multiple Sclerosis (MS). Purpose: to carry out a bibliographic review and group information related...
Abstract Introduction: Multiple sclerosis (MS) is a chronic disease of the central nervous system that mainly affects young adults, promoting a great impact on functionality. Fatigue is a very common symptom, associated with multiple impairments in sensitivity, muscle activity, neuromotor control, balan...
Objetivo: Avaliar o impacto orçamentário da inclusão da cladribina oral no tratamento de esclerose múltipla remitente-recorrente em alta atividade da doença (EMRR HDA) no Sistema de Saúde Suplementar (SSS). Métodos: Foi conduzida uma análise de impacto orçamentário, sob a perspectiva do SSS, co...
BACKGROUND: Multiple sclerosis (MS) is a central nervous system disease with a high disability rate. Modern molecular biology techniques have identified a number of key genes and diagnostic markers to MS, but the etiology and pathogenesis of MS remain unknown. RESULTS: In this study, the integration of t...
There is increasing evidence that neurofilament light chain (NF-L) can be considered as a biomarker for neuro-axonal damage. This polypeptide can be released into the cerebrospinal fluid (CSF) and the blood, where it can be quantified. The concentration of NF-L is elevated in patients with multiple scler...
Cognitive impairment and deficits in Social Cognition (SC) are frequent in patients with Multiple Sclerosis (MS). The aim of the present work is to study SC in patients with early MS and to analyze its neuroanatomical correlation. Thirty-four patients with relapsing remitting MS, with ≤ 2 years of dise...
En la esclerosis múltiple se pierde la tolerancia inmunológica a las vainas de mielina. Los virus pueden intervenir en su etiopatogenia. La actual pandemia de COVID-19 puede incrementar los casos y exacerbar los brotes de esclerosis múltiple(AU)...
