BACKGROUND Cannabinoid compounds have been approved as prescription drugs for treating various human ailments. However, the production using both microbial and plant-based sources is timeconsuming and expensive because their yield is extremely low. Tetraketide synthase (TKS), the key enzyme in the biosyn...
Hydrogels are three-dimensional networks of hydrophilic polymers. In general, these structures can be soft, elastic, porous and can absorb high quantities of water. Due to these characteristics, there is a growing interest in the use of hydrogels in diverse areas, from bioremediation to applications in t...
BACKGROUND Recently, nanomaterials have received much attention due to their important role in solving medical and environmental problems. In the present study, a novel nanocomposite based on mycosyn thesized bimetallic zinc-copper oxides nanoparticles, nanocellulose, and chitosan was ready through an ec...
Las hemoglobinopatías son trastornos genéticos que afectan a la molécula de hemoglobina (Hb). Las mutaciones en las cadenas a o b que alteran el tetrámero de Hb pueden modificar la capacidad de la molécula para unirse al oxígeno. Las hemoglobinopatías con baja afinidad al oxígeno pueden presentar...
SUMMARY: Traumatized bone tissue has the capacity to repair itself so that it eventually regains its almost original form, even in the case of artificially inserted implants. The process that stays at the base of the regeneration is represented by osteogenesis or remote osteogenesis. The major difference...
An, Fangyu;
Yan, Chunlu;
Li, Jiajin;
Lv, Xueying;
Wang, Caixia;
Deng, Jie;
Shi, Biao;
Zhang, Jinlong;
Che, Wenxuan;
Zheng, Wenrui.
SUMMARY: The 12C6+ heavy ion beam irradiation can cause bystander effects. The inflammatory cytokines, endocrine hormones and apoptotic proteins may be involved in 12C6+ irradiation-induced bystander effects. This study characterized the protective effects and mechanisms of Huangqi decoction (HQD) agains...
Scutellaria baicalensis/química,
Medicamentos Herbarios Chinos,
Sustancias Protectoras/administración & dosificación,
Apoptosis/efectos de los fármacos,
Apoptosis/efectos de la radiación,
Iones Pesados/efectos adversos,
Factores Inmunológicos/antagonistas & inhibidores,
Hormona Liberadora de Corticotropina,
Sistema Endocrino/efectos de los fármacos,
Sistema Endocrino/efectos de la radiación,
Ratas Wistar,
Antígeno Nuclear de Célula en Proliferación,
Riñón/efectos de los fármacos,
Riñón/efectos de la radiación,
Encéfalo/efectos de los fármacos,
Encéfalo/efectos de la radiación,
Hormona Adrenocorticotrópica,
Ensayo de Inmunoadsorción Enzimática
SUMMARY: Cisplatin (Cis) is an important chemotherapeutic agent used in cancer treatment. Males exposed to Cis were reported to exhibit testicular toxicity. Cis-induced testicular toxicity is mediated by oxidative stress, inflammation, testosterone inhibition and apoptosis. Accordingly, this study was co...
Camellia sinensis/química,
Extractos Vegetales/farmacología,
Té/química,
Infliximab/farmacología,
Cisplatino/toxicidad,
Testículo/efectos de los fármacos,
Recuento de Espermatozoides,
Factor de Necrosis Tumoral alfa/antagonistas & inhibidores,
Apoptosis,
Estrés Oxidativo,
Inflamación,
Ratas Sprague-Dawley,
Extractos Vegetales/química,
Inmunohistoquímica,
Malondialdehído/análisis,
Glutatión/análisis,
Testículo/patología
SUMMARY: Mormodica balsamina is a valuable medicinal plant that is used to treat wounds and inflammation; its leaves are also used as an antibiotic and in the treatment of stomach pain. This study was conducted to determine the anti-ulcer activity of methanolic leaf extract of Mormodica balsamina on etha...
Momordica/química,
Momordica balsamica,
Extractos Vegetales/administración & dosificación,
Hojas de la Planta,
Etanol/toxicidad,
Úlcera Gástrica/tratamiento farmacológico,
Mucosa Gástrica/efectos de los fármacos,
Plantas Medicinales,
Úlcera Gástrica/inducido químicamente,
Extractos Vegetales/química,
Antiulcerosos/administración & dosificación,
Antiulcerosos/química,
Modelos Animales de Enfermedad
O hormônio antimulleriano é secretado pelas células da granulosa dos folículos que estão em desenvolvimento no ovário. Por meio da sua dosagem, é possível avaliar a reserva ovariana. A mulher tem seu número máximo de oócitos no perío- do fetal, mas, conforme o tempo passa, existe uma queda do...
El presente trabajo muestra la obtención de un material a partir de un polímero sintético (TerP) y otro natural, mediante entrecruzamiento físico y su caracterización fisicoquímica y biológica, con el fin de emplearlos para regeneración de tejido óseo. Las membranas fueron obtenidas por l...
Cromatografía en Gel,
Diferenciación Celular,
Ensayo de Materiales,
Espectroscopía Infrarroja por Transformada de Fourier,
Huesos/química,
Materiales Biocompatibles/síntesis química,
Materiales Biocompatibles/toxicidad,
Osteogénesis,
Polímeros/química,
Polímeros/toxicidad,
Quitosano/química,
Quitosano/toxicidad,
Regeneración Ósea,
Resonancia Magnética Nuclear Biomolecular,
Técnicas de Cultivo de Célula
