El estudio de las estrategias neurales para la organización del comportamiento en vertebrados constituye un desafío mayor para la Neurociencia. El avance del conocimiento en este campo depende de manera crítica de la utilización de modelos experimentales adecuados que admitan múltiples niveles de an...
Abstract Background: Crocin is reported to have a wide range of biological activities such as cardiovascular protection. Recent epidemiologic studies have shown that exercise reduces cardiovascular morbidity and mortality in the general population. Objective: The aim of this study was to evaluate the e...
Abstract Background: The dietary limitation during pregnancy influences the growth and development of the fetus and offspring and their health into adult life. The mechanisms underlying the adverse effects of gestational protein restriction (GPR) in the development of the offspring hearts are not well u...
ABSTRACT BACKGROUND Ischemia/reperfusion causes organ damage but it is mandatory in hepatic transplantation, trauma and other complex liver surgeries, when Pringle maneuver is applied to minimize bleeding during these procedures. It is well known that liver ischemia/reperfusion leads to microcirculator...
Alanina Transaminasa/sangre,
Aspartato Aminotransferasas/sangre,
Modelos Animales de Enfermedad,
Hipotermia Inducida,
Fallo Hepático Agudo/etiología,
Fallo Hepático Agudo/patología,
Fallo Hepático Agudo/prevención & control,
Necrosis,
Ratas Wistar,
Daño por Reperfusión/complicaciones,
Daño por Reperfusión/patología,
Índice de Severidad de la Enfermedad
ABSTRACT BACKGROUND Leathery Murdah, Terminalia coriacea (Roxb.) Wight & Arn. from family Combretaceae is used in Ayurveda and Siddha traditional systems of medicine to heal ulcers. OBJECTIVE The present study was conducted to assess the gastroprotective effect and understand the fundamental mecha...
Antiinflamatorios no Esteroideos,
Antiulcerosos/administración & dosificación,
Aspirina,
Modelos Animales de Enfermedad,
Relación Dosis-Respuesta a Droga,
Mucosa Gástrica/efectos de los fármacos,
Extractos Vegetales/administración & dosificación,
Ratas Wistar,
Úlcera Gástrica/inducido químicamente,
Úlcera Gástrica/tratamiento farmacológico,
Terminalia/química
ABSTRACT In this study, we proposed that administration of hippocampal growth hormone in ageing animals with growth hormone deficiency can compensate long-term potentiation and synaptic plasticity in nucleus basalis magnocellularis (NBM)-lesioned rats. Aged male Wistar rats were randomly divided into six...
Menezes-Rodrigues, Francisco Sandro;
Ferraz, Renato Ribeiro Nogueira;
Oliveira, Alex Sandro Felisberto;
Silva, Marcos José da;
Bergantin, Leandro Bueno;
Ambrósio, Ricardo Thiago Paniza;
Fantoni, Alessandra de Oliveira;
Paula, Luciana de;
Errante, Paolo Ruggero;
Serinolli, Mário Ivo;
Caricati-Neto, Afonso.
Introdução: A hipertensão arterial é um dos fatores de risco para doenças cardiovasculares, estando diretamente associada ao elevado consumo de sódio. Objetivo: Avaliar os níveis de marcadores de lesão hepática, renal e cardíaca em
ratos hipertensos comparados aos seus controles normotensos, tr...
Ratas Wistar,
28573,
d0069730,
Biomarcadores,
Suplementos Dietéticos,
Cloruro de Sodio Dietético,
Creatina Quinasa/sangre,
L-Lactato Deshidrogenasa/sangre,
Ácido Úrico/sangre,
Aspartato Aminotransferasas/sangre,
Fosfatasa Alcalina/sangre,
Frecuencia Cardíaca
Introdução: O Enriquecimento ambiental (EA) tem sido estudado em reabilitação para diversas patologias. Objetivo: investigar os efeitos do EA em ratos wistar jovens submetidos ao status epilepticus, sobre os padrões de comportamento e ansiedade. Métodos: Estudo longitudinal com 40 ratos, submetidos...
ABSTRACT Objective To evaluate the action of vanillin (Vanilla planifolia) on the morphology of tibialis anterior and soleus muscles after peripheral nerve injury. Methods Wistar rats were divided into four groups, with seven animals each: Control Group, Vanillin Group, Injury Group, and Injury + Van...
Antiinflamatorios/farmacología,
Benzaldehídos/farmacología,
Tejido Conectivo/efectos de los fármacos,
Músculo Esquelético/efectos de los fármacos,
Neuropatía Ciática/patología,
Tejido Conectivo/patología,
Modelos Animales,
Fibras Musculares Esqueléticas/efectos de los fármacos,
Músculo Esquelético/patología,
Distribución Aleatoria,
Ratas Wistar,
Neuropatía Ciática/rehabilitación