LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Hipogamaglobulinemia e rituximabe: relato de casos

Souza, Márcio Niemeyer; Ribeiro, Luciana Costa; Ulaf, Raisa Gusso; Nunes, Thyago Alves; Mansour, Eli.

Arq Asma Alerg Imunol; 7 (3), 2023

Secondary immunodeficiency can result from neoplasms, infections, or immunosuppressive therapy. Rituximab (RTX) is an anti-CD20 antibody that depletes B lymphocytes and can induce symptomatic hypogammaglobulinemia. We report 3 cases of symptomatic hypogammaglobulinemia associated with the use of RTX. In ...

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Characteristics of patients with hypersensitivity reactions to chemotherapeutic and biological agents and desensitization behavior

Ardila, Juan Camilo; Castillo, Diana Maria Martinez; Calle, Ana Maria; Chinchilla, Carlos.

Arq. Asma, Alerg. Imunol; 7 (2), 2023

Introduction: Hypersensitivity to chemotherapeutic and biological agents has increased in recent years due to their frequent use. Avoidance has been the first line of defense, leading to decreased treatment efficacy and increased adverse events. Objective: To characterize the sociodemographic and clinica...

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Efecto del Rituximab sobre los niveles circulantes de citocinas y quimiocinas producidas o no por los linfocitos B en pacientes con Artritis Reumatoide

Segura-González, Angie Katherine; Tovar-Sánchez, Catherin; Franco-Cortés, Manuel A; Rodríguez-Camacho, Luz Stella.

Iatreia; 35 (3), 2022

La Artritis Reumatoide (AR) es una enfermedad autoinmune frecuente, caracterizada por inflamación crónica en las articulaciones que puede progresar a la destrucción ósea. Aunque la fisiopatología de la AR no es clara, se ha visto que las células T y las células B desempeñan un importante papel en...

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