SUMMARY: Estradiol and progesterone receptors play an essential role in the changes occurring in the uterus during the estrus cycle in dogs (Canis lupus familiaris). In order to investigate the potential effect of progestational agent medroxyprogesterone acetate (MPA) when is used during anestrus on the ...
:Breast cancer is the object of thousands of studies worldwide. Nevertheless, few tools are available to corroborate
prediction of response to neoadjuvant chemotherapy. Artificial intelligence is being researched for its potential utility in several fields of knowledge, including oncology. The developme...
Neoplasias de la Mama/tratamiento farmacológico,
Terapia Neoadyuvante,
Inteligencia Artificial,
Estrógenos/metabolismo,
Progesterona/metabolismo,
Antígeno Ki-67/metabolismo,
Receptor ErbB-2/metabolismo,
Estudios Retrospectivos,
Redes Neurales de la Computación,
Recurrencia Local de Neoplasia,
Antineoplásicos/uso terapéutico
Chagas, Diego Cipriano;
Barros-Oliveira, Maria da Conceição;
Lopes-Costa, Pedro Vitor;
Pereira, Renato de Oliveira;
Melo, Mariella de Almeida;
Costa-Silva, Danylo Rafhael;
Borges, Carine Soares;
Viana, Jackeline Lopes;
Santos, Alesse Ribeiro dos;
Facina, Gil;
Silva, Benedito Borges da.
OBJECTIVES: Aromatase inhibitors are the first-choice drugs for the treatment of hormone sensitive breast cancer. However, in addition to the scarcity of studies, there are controversies about their effects on vaginal epithelial cell proliferation in rats, especially those in persistent estrus. METHODS:...
El adenocarcinoma NOS (no especificado de otra manera) es un tumor salival sin patrón especial poco mencionado en la literatura; su diagnóstico es un desafío porque estructuralmente no se identifica con otros carcinomas salivales más definidos. Por otro lado, Ki67 es un marcador de proliferación cel...
Neoplasias de la Parótida/metabolismo,
Neoplasias de la Parótida/patología,
Neoplasias de la Parótida/diagnóstico,
Adenocarcinoma/metabolismo,
Adenocarcinoma/patología,
Adenocarcinoma/diagnóstico,
Antígeno Ki-67/metabolismo,
Mucina-1/metabolismo,
Proliferación Celular,
Pronóstico,
Inmunohistoquímica,
Biomarcadores de Tumor,
Neoplasias de las Glándulas Salivales
ABSTRACT Background: Intestinal diversions have revolutionized the treatment of morbid obesity due to its viability and sustained response. However, experimental studies suggest, after these derivations, a higher risk of colon cancer. Aim: To analyze the histological and immunohistological changes that...
Abstract Objective To identify the biomarkers of response to neoadjuvant chemotherapy in early luminal breast cancer. Methods A cross-sectional study that included all patients with early or locallyadvanced luminal breast cancer submitted to neoadjuvant chemotherapy between 2013 and 2014. Demographic...
Antineoplásicos/uso terapéutico,
Neoplasias de la Mama/tratamiento farmacológico,
Neoplasias de la Mama/genética,
Quimioterapia Adyuvante,
Estudios Transversales,
Expresión Génica,
Antígeno Ki-67/genética,
Antígeno Ki-67/metabolismo,
Menopausia,
Persona de Mediana Edad,
Terapia Neoadyuvante,
Receptor ErbB-2/genética,
Receptor ErbB-2/metabolismo,
Receptores de Estrógenos/genética,
Receptores de Estrógenos/metabolismo,
Receptores de Progesterona/genética,
Receptores de Progesterona/metabolismo
ABSTRACT: The present study aimed to investigate the occurrence of mandibular canal alterations in regions with dental inflammation by means of cone beam computed tomography (CBCT). A database of 2,484 CBCTs was reviewed for identifying dental inflammation in mandibular alveolar ridges. The final sample ...
Abstract Purpose To investigate the effects of pine needle extract (PNE) on the expression of proliferating cell nuclear antigen (PCNA) and Ki-67 during liver regeneration induced by 70% partial hepatectomy (PH) in rat. Methods Forty-eight male rats (SD, 7 weeks) had surgery (70% PH). They were randoml...
Proliferación Celular,
Hepatectomía/métodos,
Antígeno Ki-67/efectos adversos,
Antígeno Ki-67/metabolismo,
Regeneración Hepática/efectos de los fármacos,
Índice Mitótico,
Pinus/química,
Extractos Vegetales/farmacología,
Antígeno Nuclear de Célula en Proliferación/efectos de los fármacos,
Antígeno Nuclear de Célula en Proliferación/metabolismo,
Ratas Sprague-Dawley,
Factores de Tiempo
Background: The capacity for prognostic prediction of cutaneous melanoma, one of the most aggressive cancers, is still difficult due to the tumor heterogeneity and lack of reliable tumor markers. The objective of this study is to correlate, through immunohistochemistry, a Ki-67 and Kindlin-1 staining in ...
SUMMARY OBJECTIVE: Ki-67 is a nuclear protein associated with cellular proliferation in normal or leukemic conditions that can help identify more aggressive diseases and is usually evaluated with immunohistochemistry. The aim of this was to assess Ki-67 expression on mature B-cell neoplasms samples with...
