Results: 12

Plano de ação nacional de prevenção e controle da resistência aos antimicrobianos no âmbito da saúde única: 2018-2022

No presente documento, é apresentado o Plano Estratégico do PAN-BR (formato executivo), que contém 14 Objetivos Principais, 33 Intervenções Estratégicas e 75 Atividades, alinhados aos 5 Objetivos Estratégicos do Plano de Ação Global....

Antimicrobial and antibiofilm activities of phenolic compounds extracted from Populus nigra and Populus alba buds (Algeria)

The interest of this work is the discovery of new antimicrobial agents of plant origin to inhibit the formation of microbial biofilms. The present research was conducted to identify and quantify the phenolic compounds extracted from Populus nigra and Populus alba buds harvested in the area of Tizi-Ouzou ...

The use of antimicrobials in septic patients with acute kidney injury

J. bras. nefrol; 39 (3), 2017
Abstract Sepsis is the most common cause of death in critically ill patients and it may be associated with multiorgan failure, including acute kidney injury (AKI). This situation can require acute renal support and increase mortality. Therefore, it is essential to administrate antimicrobials in dosis to ...

Phytoconstituents from Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) and antimicrobial activity of pheophytin a

Braz. j. pharm. sci; 51 (4), 2015
abstract Sidastrum micranthum (A. St.-Hil.) Fryxell, a member of the Malvaceae family, is called malva preta in Brazil. As this species is commonly used to treat bronchitis, cough, and asthma, better knowledge of its chemical compounds is important. The phytochemical study of its hexane extract, using ch...

Development and validation of a rapid turbidimetric assay to determine the potency of norfloxacin in tablets

Braz. j. pharm. sci; 51 (3), 2015
Norfloxacin is one of the first commercially available (and most widely used) fluoroquinolone antibiotics. This paper reports the development and validation of a simple, sensitive, accurate and reproducible turbidimetric assay method to quantify norfloxacin in tablets formulations in only 4 hours. The bi...

Quinolonas: revision historica
Quinolones: historic review

Medicina (B.Aires); 59 (supl.1), 1999
En las últimas tres décadas, se produjo el desarrollo farmacoterapéutico de las quinolonas. El primer producto, que se incorporó al comercio en el año 1965, fue el ácido nalidíxico (quinolona de primera generación) y luego, los químicos sintetizaron varios miles de derivados modificando primaria...

Farmacocinetica de la trovafloxacina: su significado clinico
Pharmacokinetics of trovafloxacin: its clinical significance

Medicina (B.Aires); 59 (supl.1), 1999
La trovafloxacina se absorbe rápidamente después de su administración oral y llega a su concentración sérica máxima alrededor de una hora. La alatrofloxacina es la prodroga que, al administrarse por vía endovenosa se hidrolisa rápidamente a su estado original. La biodisponibilidad es equivalente ...

Indice inhibitorio (II) e índice bactericida (IB): parámetros que favorecen la comparación de la actividad de agentes antimicrobianos
Inhibitory index (II) and bactericidal index (BI): parameters that allow antimicrobial agents activity comparison

Rev. chil. infectol; 14 (3), 1997
Se define el indice inhibitorio (11) como la relación entre la concentración plasmática máxima (CMáx) que alcanza un agente antibacteriano in vivo y su actividad inhibitorio ín vitro, expresada en forma de CIM. Al mismo tiempo, el indice bactericida (IB) se define como la relación entre la CMáx d...