Introdução: A fitoterapia se baseia na utilização de plantas medicinais, através de diferentes formulações farmacêuticas com fins terapêuticos. Na Odontologia, os fitoterápicos têm sido alvo de estudos, devido suas propriedades benéficas, além de apresentarem biocompatibilidade, baixo custo ...
Leaves of Croton stipulaceuswere extracted (EHex, ECHCl3and EEtOH extracts) to assesstheir antioxidant potential, anti-inflammatory activity in murine models and acute toxicity. EEtOH showed the highest effect in DPPH (37.80% inhibition), FRAP (1065.00 ± 55.30 μmolFe2+) ...
Croton/química,
Inflamación/tratamiento farmacológico,
Hojas de la Planta,
Extractos Vegetales/administración & dosificación,
Modelos Animales de Enfermedad,
Antioxidantes/administración & dosificación,
Antiinflamatorios/administración & dosificación,
Extractos Vegetales/química,
Antioxidantes/química,
Antiinflamatorios/química,
Fenoles/análisis
Jadidian, Faezeh;
Amirhosseini, Mehraban;
Abbasi, Mina;
Faal Hamedanchi, Neda;
Zerangian, Nasibeh;
Erabi, Gisou;
Abdi, Amir;
Hosseini, Mahdieh;
Torabi, Kimia;
Shahini, Alireza;
Aghakhani, Ava;
Norouzkhani, Narges;
Kheirandish, Ali;
Rashidi, Sara;
Deravi, Niloofar;
Aleebrahim Dehkordi, Elahe.
Age-related neurological disorders (ANDs), including neurodegenerative diseases, are complex illnesses with an increasing risk with advancing years. The central nervous system's neuropathological conditions, including oxidative stress, neuroinflammation, and protein misfolding, are what defin...
Introducción: La enfermedad de Caffey es una patología ósea inflamatoria, rara, autolimitada, casi exclusiva de lactantes. Objetivos: Jerarquizar el abordaje diagnóstico de una patología poco frecuente. Caso clínico: 4 meses 22 días, varón, consulta por irritabilidad y edema de miembro inferior i...
As doenças respiratórias são consideradas doenças graves e potencialmente deletérias. Dentre elas, a asma e a bronquite crônica caracterizam-se como disfunções respiratórias que ameaçam constantemente o bem-estar dos gatos. Os pacientes apresentam mudanças na estrutura respiratória, reversív...
Munhoz, Lauriene Luiza de Souza;
Guillens, Luiz Carlos;
Alves, Beatriz Candido;
Nascimento, Maria Gabriela Oliveira Ferreira do;
Meneguin, Andréia Bagliotti;
Carbinatto, Fernanda Mansano;
Arruda, Gabriela;
Barud, Hernane da Silva;
Aro, Andrea de;
Casagrande, Laura de Roch;
Silveira, Paulo Cesar Lock;
Andrade, Thiago Antônio Moretti;
Santos, Glaucia Maria Tech dos;
Caetano, Guilherme Ferreira.
Purpose: Bacterial cellulose (BC) has shown high capacity for the treatment of wounds and burns, providing a moisty environment. Calcium alginate can be associated with BC to create gels that aid in wound debridement and contribute to appropriate wound healing. This study is aimed at characterizing and e...
Neri, Jannyely Moreira;
Siqueira, Paula Emília Apolônio;
Oliveira, Ana Luiza Cabral de Sá Leitão;
Araújo, Renata Mendonça;
Araújo Júnior, Raimundo Fernandes de;
Martins, Agnes Andrade;
Marques, Isabelle de Lima;
Silva, Rafaela Alcindo;
Araújo, Aurigena Antunes de;
Menezes, Fabrício Gava.
Purpose: Bioactive molecules are relevant to fight cancer and associated conditions. Quinoxaline is a privileged N-heterocycle, notably as anticancer agents. Herein, we report the evaluation of the quinoxaline derivatives DEQX and OAQX as anticancer agents, as well as in function of their anti-inflammato...
Pajolli, Pedro;
Kawano, Paulo Roberto;
Yamamoto, Hamilto;
Guerra, Rodrigo;
Moraes, Bruno Matos;
Reis, Leonardo Oliveira;
Ordones, Flavio Vasconcelos;
Fugita, Oscar Eduardo Hidetoshi;
Melchert, Alessandra;
Amaro, João Luiz.
Purpose: Hibiscus sabdariffa (HS) extract has several health benefits and anti-obesogenic effects. The aim of the present study was to assess whether the medicinal properties attributable to HS would prevent or mitigate bladder changes induced by obesity in an experimental model. Methods: Forty-eight mal...
Purpose: To investigate the impact of the Chinese medicine compound Ento-PB on oxazolone (OXZ)-induced ulcerative colitis (UC) in rats. Methods: UC rats induced by OXZ were treated with Ento-PB. The damage to the colon was assessed using several measures, including the disease activity index (DAI), colon...
Purpose: Lipopolysaccharides is well-known in the acute renal injury process. It causes widespread activation of inflammatory cascades. Tumor necrosis factor (TNF)-α and interleukin (Il)-6 are essential proinflammatory cytokines that can induce the production of other cytokines in host response. Adalimu...