Myrtus communis
L., commonly known as true myrtle, is a medicinal plant native to the
Mediterranean area. Since ancient times, the inhabitant
s of this area have been using it for its cultural and
medicinal properties. Because of the vast diversity of biomolecules in its aerial parts, ...
SUMMARY: This study evaluated the phytochemical screening, antioxidant capacity, and in vitro anticancer activities of four plants namely, Gypsophila capillaris, Anabasis lachnantha, Haloxylon salicornicum, and Horwoodia dicksoniae which belong to four different families: Caryophyllaceae, Amaranthaceae, ...
Plantas Medicinales/química,
Metabolómica,
Antioxidantes/química,
Antineoplásicos/química,
Cromatografía Líquida de Alta Presión,
Técnicas In Vitro,
Fenoles/análisis,
Antocianinas/análisis,
Saponinas/análisis,
Células Hep G2/efectos de los fármacos,
Células MCF-7/efectos de los fármacos,
Antioxidantes/farmacología,
Antineoplásicos/farmacología,
Arabia Saudita,
Fitoquímicos
This study reports the biotechnological importance of seven Lippia albaspecimens collected in different places in Brazil, and evaluation of some activities as larvicidal against Aedes spp., antifungal against dermatophytes; cytotoxicity against SNB-19 (astrocytoma), HCT-116 (human col...
Lippia/química,
Aceites Volátiles/química,
Antineoplásicos/química,
Plantas Medicinales,
Brasil,
Control Biológico de Vectores,
Terpenos/análisis,
Biotecnología,
Larvicidas,
Antifúngicos,
Inhibidores de la Colinesterasa,
Antineoplásicos/farmacología,
Aceites Volátiles/farmacología,
Línea Celular Tumoral/efectos de los fármacos,
Aedes/efectos de los fármacos
Several investigations have demonstrated Dicranopteris linearis (Burm.f.) Underw. (Gleicheniaceae) plant extracts possess numerous health-promoting properties. This review is aimed to summarize and highlight the potential possess by D. linearisto be developed into future pharmacological entity especiall...
In the present study, we investigated the antiproliferative activity of essential oil from leaves of Melissa officinalis L. grown in Southern Bosnia and Herzegovina. In vitro evaluation of antiproliferative activity of the M. officinalis essential oil was carried out on three human tumor cell lines: MCF-...
Melissa,
Aceites Volátiles/farmacología,
Aceites Volátiles/química,
Proliferación Celular/efectos de los fármacos,
Línea Celular Tumoral/efectos de los fármacos,
Antineoplásicos/farmacología,
Antineoplásicos/química,
Hojas de la Planta,
Técnicas In Vitro,
Cromatografía de Gases y Espectrometría de Masas,
Monoterpenos/análisis,
Sesquiterpenos/análisis,
Células Tumorales Cultivadas
Irrespective of progressive treatments, cancer remains to have the utmost rate of treatment failure due to numerous reasons associated. In recent years, the use of traditional medicine in cancer research has established considerable interest. Natural products represent an amazing source for cancer therap...
Cell cycle control genes are frequently mutated in cancer cells, which usually display higher rates of proliferation than normal cells. Dysregulated mitosis leads to genomic instability, which contributes to tumor progression and aggressiveness. Many drugs that disrupt mitosis have been studied because t...
This review will discuss the contributions of marine natural molecules, a source only recently found to have pharmaceutical prospects, to the development of anticancer drugs. Of the seven clinically utilized compounds with a marine origin, four are used for the treatment of cancer. The development of the...
Antineoplásicos/química,
Antineoplásicos/farmacología,
Antineoplásicos/uso terapéutico,
Organismos Acuáticos/química,
Biotecnología/métodos,
Brentuximab Vedotina,
Citarabina/química,
Desarrollo de Medicamentos/métodos,
Descubrimiento de Drogas,
Furanos/química,
Inmunoconjugados/química,
Inmunoconjugados/farmacología,
Inmunoconjugados/uso terapéutico,
Cetonas/química,
Neoplasias/tratamiento farmacológico,
Océanos y Mares,
Trabectedina/química
A novel heterometallic metal-porphyrinic framework (MPFs) built from Y and K ions as nods and meso-tetra(4-carboxyphenyl)porphyrin as linkers has been successfully synthesized and characterized. The single crystal X-ray diffraction indicated that this complex 1 exhibited a bilayered architecture of the p...
Antineoplásicos/química,
Antineoplásicos/farmacología,
Neoplasias de la Mama/tratamiento farmacológico,
Línea Celular Tumoral,
Complejos de Coordinación/química,
Complejos de Coordinación/farmacología,
Cristalografía por Rayos X,
Formazáns,
Estructuras Metalorgánicas/química,
Estructuras Metalorgánicas/farmacología,
Porfirinas/química,
Valores de Referencia,
Reproducibilidad de los Resultados,
Sales de Tetrazolio
ABSTRACT Scientific and technological breakthroughs have compelled the current players in drug discovery to increasingly incorporate knowledge-based approaches. This evolving paradigm, which has its roots attached to the recent advances in medicinal chemistry, molecular and structural biology, has unprec...
