Results: 3

Ameliorating effects of ethanol extract of root bark of Salacia nitida on blood electrolyte and renal perturbations in Plasmodium berghei-infected mice

Abstract Malaria, a disease of public health concern is a known cause of kidney failure, and dependence on herbal medicines for its treatment is increasing due to the high cost of drugs. So this study is designed to evaluate the ameliorating effect of ethanol extract from Salacia nitida root bark on elec...

Ácido acetilsalicílico e terapia combinada com dihidroartemisinina na síndrome do desconforto respiratório agudo associado à malária: análise da função pulmonar e do processo inflamatório

A malária é uma doença parasitária predominante em países de clima tropical e subtropical, que pode levar a complicações como malária cerebral, anemia grave e síndrome do desconforto respiratório agudo (SDRA). A SDRA é resultante da exacerbação do processo inflamatório e do sequestro de eri...

Artesunate promotes Th1 differentiation from CD4+ T cells to enhance cell apoptosis in ovarian cancer via miR-142

Braz. j. med. biol. res; 52 (5), 2019
The aim of this study was to evaluate the influence of artesunate on Th1 differentiation and its anti-tumor effect on ovarian cancer. A Murine ovarian cancer model was established by ID8 cells transplantation. The expression of miR-142 and Sirt1 proteins in peripheral CD4+ T cells were quantified with qR...