Introducción:
El sarcoma de Ewing es un tumor maligno de alto grado con localización principalmente ósea; se han reportado aproximadamente 12% con presentación extra-esquelética. Actualmente, existen alrededor de 20 casos descritos en la literatura con origen mediastinal y 10 casos con origen pulm...
Sarcoma de Ewing/diagnóstico,
Derrame Pleural,
Neoplasias Óseas,
Neoplasias del Mediastino/cirugía,
Agroquímicos,
Diagnóstico por Imagen,
Toracotomía,
Esternotomía,
Biopsia,
Biomarcadores de Tumor,
Linfadenopatía,
Síndrome de la Vena Cava Superior,
Disnea,
Dolor en el Pecho
INTRODUCTION: Breast cancer is one of the main causes of death in women. Luminal tumors A and B show good response with hormonal treatments, tumors that overexpress HER-2 can be treated with monoclonal antibodies, whereas triple negative tumors have few treatments available because they present low or ab...
SUMMARY: The calcium-activated chloride channel (CLCA2) performs a vital function in the intricate process of tumorigenesis. Using a bioinformatics analysis system, we conducted a pan-cancer investigation on CLCA2 to explore its association with tumor prognosis and its involvement in immunology. In order...
SUMMARY: Esophageal cancer is one of the most aggressive gastrointestinal cancers. Invasion and metastasis are the main causes of poor prognosis of esophageal cancer. SPRY2 has been reported to exert promoting effects in human cancers, which controls signal pathways including PI3K/AKT and MAPKs. However,...
SUMMARY: Calcium-activated chloride channel regulator 1 (CLCA1) is associated with cancer progression. The expression and immunologic function of CLCA1 in stomach adenocarcinoma (STAD) remain unclear. In this investigation, the expression of CLCA1 in STAD tissues and its involvement in the progression an...
Neoplasias Gástricas/metabolismo,
Adenocarcinoma/metabolismo,
Canales de Cloruro/metabolismo,
Inmunohistoquímica,
Pronóstico,
Canales de Cloruro/genética,
Mutación,
Análisis de Supervivencia,
Neoplasias Gástricas/inmunología,
Adenocarcinoma/inmunología,
Canales de Cloruro/inmunología,
Biomarcadores de Tumor,
Biología Computacional
Ahmad, M;
Hameed, Y;
Khan, M;
Usman, M;
Rehman, A;
Abid, U;
Asif, R;
Ahmed, H;
Hussain, M S;
Rehman, J U;
Asif, H M;
Arshad, R;
Atif, M;
Hadi, A;
Sarfraz, U;
Khurshid, U.
Abstract Cancer is a fatal malignancy and its increasing worldwide prevalence demands the discovery of more sensitive and reliable molecular biomarkers. To investigate the GINS1 expression level and its prognostic value in distinct human cancers using a series of multi-layered in silico approach may help...
RESUMEN El objetivo del estudio fue conocer el perfil inmunohistoquímico del cáncer de mama e identificar el subgrupo HER2 low en la macrorregión norte del Perú. Se realizó un estudio transversal con una muestra de 1176 pacientes atendidos en el Instituto Regional de Enfermedades Neoplásicas Norte ...
O fenômeno conhecido como multidrug resistance (MDR) observado no câncer é
um grande desafio na busca por terapias mais eficientes. Esse fenótipo é o resultado da
combinação de vários fatores, como a alta expressão de bombas de efluxo da superfamília
de proteínas transportadoras ABC, que imped...
Abstract Objective This study aimed to correlate the expression, by immunohistochemistry, of the proteins OPN, ABCB5, and WNT3A from anatomopathological materials obtained from paraffin blocks, slides, or both, from patients with osteosarcoma (OS), analyzing epidemiological characteristics, as well as t...
Los tumores de células germinales (TCGs) se forman a partir de células embrionarias y generalmente se presentan en pacientes de entre 11 y 30 años de edad. Los TCG pue-den presentarse como tumores extragonadales, siendo el mediastino anterior el sitio más común en el 50 a 70% de los casos...
