Results: 4

Stereological analysis of elastic fibers of the corpus cavernosum of rats during the aging process

Acta cir. bras; 34 (8), 2019
Abstract Purpose To evaluate changes in the quantity of elastic fibers in the corpora cavernosa of rats during the natural aging process, and to assess the degree of this change by determining volumetric density (Vv) at different ages via stereological analysis. Methods Forty-eight rats, raised under...

Endothelial assessment of donated tectonic corneas: a viable option for posterior lamellar transplantation

Arq. bras. oftalmol; 81 (2), 2018
ABSTRACT Purpose: Donated corneas are classified as tectonic if there are defects within any layers of the cornea which would prevent a satisfactory visual outcome after transplantation. This study aimed to evaluate whether some tectonic corneas have sufficient endothelial characteristics to allow their...

Mechanism of hif-1α mediated hypoxia-induced permeability changes in bladder endothelial cells

Braz. j. med. biol. res; 51 (2), 2018
This study aimed to investigate the mechanism of hypoxia-inducible factor-1 alpha (HIF-1α) mediated hypoxia-induced permeability changes in bladder endothelial cells. Models of in vitro hypoxic cell culture of bladder cancer, bladder cancer cells with low HIF-1α expression and HIF-1α RNA i...

Efeitos das nanocápsulas de núcleo lipídico contendo acetileugenol em melanomas: estudos in vivo e in vitro

O melanoma é uma neoplasia de pele invasivo, com maior taxa de morte, sem tratamento efetivo. Nanocápsulas poliméricas de núcleo lipídico (LNC) tem sido empregadas com sucesso como carreadores de fármacos hidrofóbicos. Como o eugenol é um composto hidrofóbico com atividades antiproliferativas e ...