Results: 20

Combined administration of gallic acid and glibenclamide mitigate systemic complication and histological changes in the cornea of diabetic rats induced with streptozotocin

Acta cir. bras; 39 (), 2024
Purpose: To determine the effect of gallic acid or its combination with glibenclamide on some biochemical markers and histology of the cornea of streptozotocin (STZ) induced diabetic rats. Methods: Following induction of diabetes, 24 male albino rats were divided into four groups of six rats each. Group...

Bilateral ocular deposit of chlorpromazine

Rev. bras. oftalmol; 81 (), 2022
ABSTRACT Chlorpromazine is a medication widely used in psychiatry for the treatment of psychoses, especially schizophrenia. Since 1964, published articles have been correlating this medication with the appearance of ocular alterations. In this paper, we report the case of a 65-year-old patient with ocula...

Ocular surface findings in impression cytology after interferon a2b or mitomycin C in rabbits

Rev. bras. oftalmol; 80 (4), 2021
ABSTRACT Objective: To describe ocular surface findings in impression cytology obtained from healthy rabbit conjunctiva treated with interferon alpha-2b eyedrop, and compare them to findings after use of mitomycin C 0.02%. Methods: An experimental study using a rabbit model was performed between Septem...

Investigating the effect of intracameral cefuroxime on oxidative stress and apoptosis in the rat cornea

Arq. bras. oftalmol; 82 (4), 2019
ABSTRACT PURPOSE: We examined the effect of intracameral administration of cefuroxime on oxidative stress and endothelial apoptosis in rat corneal tissue. METHODS: In total, 30 rats were divided into 3 groups of 10 rats each (intracameral administration of cefuroxime 0.1 mg/0.01 mL (cefuroxime group); ...

Accelerated collagen cross-linking in the management of advanced Acanthamoeba keratitis

Arq. bras. oftalmol; 82 (2), 2019
ABSTRACT Purpose: To report our initial experience in the treatment of Acanthamoeba keratitis with accelerated corneal collagen cross-linking. Methods: Retrospective chart review of patients diagnosed with Acanthamoeba keratitis with progressive corneal melting who were treated with accelerated collage...

Effects of topical and subconjunctival use of bevacizumab on corneal neovascularization in rabbits' eyes

Arq. bras. oftalmol; 80 (4), 2017
ABSTRACT Purpose: To evaluate and compare the effects of topical application and subconjunctival injection of bevacizumab on corneal neovascularization (CNV) in rabbits' eyes after chemical burning of the cornea. Methods: The animals were randomly distributed into four groups of five animals. In one gr...

Penetration of 0. 3% ciprofloxacin, 0. 3% ofloxacin, and 0. 5% moxifloxacin into the cornea and aqueous humor of enucleated human eyes

Braz. j. med. biol. res; 50 (7), 2017
We aimed to quantify the penetration of ciprofloxacin, ofloxacin, and moxifloxacin into the cornea and aqueous humor of cadaver eyes. A total of 60 enucleated eyes, not eligible for corneal transplantation, were divided into three groups and immersed in commercial solutions of 0.3% ciprofloxacin, 0.3% of...

Six-month outcomes of corneal crosslinking with dextran-free isotonic riboflavin solution

Arq. bras. oftalmol; 79 (3), 2016
ABSTRACT Purpose: To analyze the short-term clinical and topographic outcomes in patients with keratoconus after corneal collagen cross-linking treatment (CXL) with dextran-free isotonic riboflavin solution. Methods: In this retrospective case series, 26 eyes from 26 patients with keratoconus were stud...

Corneal collagen cross-linking for progressive keratoconus in patients aged 9 to 14

Rev. bras. oftalmol; 75 (2), 2016
RESUMO Objetivo: Determinar a segurança e eficácia do cross-linking corneano (CXL) em pacientes de 9 a 14 anos de idade com ceratocone progressivo. Métodos: Dezesseis olhos de onze pacientes (8 homens e 3 mulheres) com ceratocone progressivo foram submetidos ao CXL, de acordo com o protocolo padrão...

Investigação oftalmológica pré-clínica do óleo essencial de Origanum vulgare L. Lamiaceae

Rev. bras. oftalmol; 75 (2), 2016
RESUMO Objetivo: Avaliar a irritação ocular aguda em coelhos, após a administração tópica de óleo essencial. Métodos: Para tanto, os animais foram divididos em três grupos, cada um com três coelhos, totalizando 6 olhos por grupo, e a diferença entre eles foi a concentração utilizada ( 1, 3...