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nNav1.5 expression is associated with glutamate level in breast cancer cells

Azahar, Irfan Irsyad; Sharudin, Nur Aishah; Din, Ahmad Hafiz Murtadha Noor; Has, Ahmad Tarmizi Che; Nafi, Siti Norasikin Mohd; Jaafar, Hasnan; Mokhtar, Noor Fatmawati.
Biol. Res; 55 (), 2022
Abstract Background: Glutamate and voltage-gated sodium channels, both have been the target of intense investigation for its involvement in carcinogenesis and progression of malignant disease. Breast cancer with increased level of glutamate often metastasize to other organs (especially bone), whilst re-e...
Neoplasias de la Mama/genética, Canal de Sodio Activado por Voltaje NAV1.5/genética, Canal de Sodio Activado por Voltaje NAV1.5/metabolismo, Línea Celular Tumoral, Ácido Glutámico, ARN Interferente Pequeño
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Compound Heterozygous SCN5A Mutations in a Toddler - Are they Associated with a More Severe Phenotype?

Sacilotto, Luciana; Epifanio, Hindalis Ballesteros; Darrieux, Francisco Carlos da Costa; Wulkan, Fanny; Oliveira, Theo Gremen Mimary; Hachul, Denise Tessariol; Pereira, Alexandre da Costa; Scanavacca, Mauricio Ibrahim.
Arq. bras. cardiol; 108 (1), 2017
Abstract Compound heterozygosity has been described in inherited arrhythmias, and usually associated with a more severe phenotype. Reports of this occurrence in Brugada syndrome patients are still rare. We report a study of genotype-phenotype correlation after the identification of new variants by geneti...
Aleteo Atrial/genética, Aleteo Atrial/fisiopatología, Síndrome de Brugada/genética, Síndrome de Brugada/fisiopatología, Electrocardiografía, Predisposición Genética a la Enfermedad, Heterocigoto, Mutación, Canal de Sodio Activado por Voltaje NAV1.5/genética, Linaje, Fenotipo, Índice de Severidad de la Enfermedad
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