SUMMARY: The calcium-activated chloride channel (CLCA2) performs a vital function in the intricate process of tumorigenesis. Using a bioinformatics analysis system, we conducted a pan-cancer investigation on CLCA2 to explore its association with tumor prognosis and its involvement in immunology. In order...
SUMMARY: Calcium-activated chloride channel regulator 1 (CLCA1) is associated with cancer progression. The expression and immunologic function of CLCA1 in stomach adenocarcinoma (STAD) remain unclear. In this investigation, the expression of CLCA1 in STAD tissues and its involvement in the progression an...
Neoplasias Gástricas/metabolismo,
Adenocarcinoma/metabolismo,
Canales de Cloruro/metabolismo,
Inmunohistoquímica,
Pronóstico,
Canales de Cloruro/genética,
Mutación,
Análisis de Supervivencia,
Neoplasias Gástricas/inmunología,
Adenocarcinoma/inmunología,
Canales de Cloruro/inmunología,
Biomarcadores de Tumor,
Biología Computacional
SUMMARY: Colon adenocarcinoma (COAD) is a prevalent disease worldwide, known for its high mortality and morbidity rates. Despite this, the extent of investigation concerning the correlation between COAD's CLCA1 expression and immune cell infiltration remains insufficient. This study seeks to examine the ...
Canales de Cloruro/metabolismo,
Neoplasias del Colon/inmunología,
Adenocarcinoma/inmunología,
Biología Computacional,
Pronóstico,
Análisis de Supervivencia,
Análisis de Regresión,
Análisis Multivariante,
Inmunohistoquímica,
Canales de Cloruro/inmunología,
Neoplasias del Colon/metabolismo,
Adenocarcinoma/metabolismo
SUMMARY: We investigated Tweety Family Member 3 (TTYH3) level in lung adenocarcinoma (LUAD) and its relationship with immune infiltration in tumors by bioinformatics. Differential expressions of TTYH3 in lung cancer were analyzed with Oncomine, TIMER, GEO, UALCAN and HPA. Relationship of TTYH3 mRNA/prote...
Neoplasias Pulmonares/diagnóstico,
Neoplasias Pulmonares/inmunología,
Neoplasias Pulmonares/metabolismo,
Adenocarcinoma del Pulmón/diagnóstico,
Adenocarcinoma del Pulmón/inmunología,
Adenocarcinoma del Pulmón/metabolismo,
Canales de Cloruro/metabolismo,
Canales de Cloruro/genética,
ARN Mensajero,
Pronóstico,
Linfocitos,
Biomarcadores de Tumor
INTRODUÇÃO: A Fibrose Cística é uma doença grave e rara, que comete vários sistemas orgânicos com repercussão direta na qualidade de vida de pacientes e familiares, bem como reduz significativamente a sobrevida dos portadores da enfermidade. Tezacaftor-ivacaftor têm mecanismos de ação compleme...
INTRODUÇÃO: A Fibrose Cística é uma doença grave e rara, que acomete vários sistemas orgânicos com repercussão direta na qualidade de vida de pacientes e familiares, bem como reduz significativamente a sobrevida dos portadores da enfermidade. Tezacaftor-ivacaftor têm mecanismos de ação complem...
Abstract Background: Osteopetrosis is a rare hereditary bone dysplasia characterized by insufficient osteoclast activity that results in increased bone mineral density. Hematopoietic stem cell transplantation (HSCT) can reverse skeletal abnormalities and restore hematopoiesis. Case report: We present t...
Abstract Chloride intracellular channel-4 (CLIC4) is regulated by p53 and tumor necrosis factor-α (TNF-α), it is linked to the increase of transforming growth factor-β (TGF-β), and myofibroblastic differentiation in skin carcinogenesis. This study analyzed the immunoexpression of CLIC...
Los canales de cloruros, de sodio, de bicarbonato y los de agua (aquaporinas) se coordinan para mantener la cubierta líquido superficial de las vías respiratorias, que es necesaria para el aclaramiento mucociliar. El mecanismo general para el transporte de electrolitos y agua depende principalmente de ...
La enfermedad de Dent es una tubulopatía recesiva ligada al cromosoma X caracterizada por proteinuria de bajo peso molecular (bpm), hipercalciuria, nefrocalcinosis o nefrolitiasis, disfunción tubular proximal e insuficiencia renal en la adultez. Las mujeres son portadoras y, en general, padecen una for...
