BACKGROUND Left ventricular aneurysm (LVA) is indicator of high morbidity in Chagas' disease. A cross-sectional study performed identified LVA in 18.8% of the chronic chagasic patients (CCP). OBJECTIVE Determine the risk of death of patients with chronic chagasic cardiopathy (CCC) and LVA in 24-year in...
SUMMARY BACKGROUND: Cardiac resynchronization therapy (CRT) is a therapeutic modality for patients with heart failure (HF). The effectiveness of this treatment for event reduction is based on clinical trials where the population of patients with Chagas' disease (DC) is underrepresented. OBJECTIVE: To e...
Abstract Introduction: Chagas disease represents an important health problem with socioeconomic impacts in many Latin-American countries. It is estimated that 20% to 30% of the people infected by Trypanosoma cruzi will develop chronic Chagas cardiomyopathy (CCC), which is generally accompanied by heart ...
Fundamento: A doença de Chagas é um problema de saúde global, sendo necessário o desenvolvimento de novos protocolos terapêuticos. Nosso grupo demonstrou recentemente que o nifurtimox associado ao dipiridamol tem efeitos curativos em camundongos com doença de Chagas aguda. Neste estudo, avaliamos o...
Abstract Background: Prognostic factors are extensively studied in heart failure; however, their role in severe Chagasic heart failure have not been established. Objectives: To identify the association of clinical and laboratory factors with the prognosis of severe Chagasic heart failure, as well as th...
Abstract Background: The outcome of Chagas disease patients after receiving implantable cardioverter defibrillator (ICD) is still controversial. Objective: To compare clinical outcomes after ICD implantation in patients with chronic Chagas cardiomyopathy (CCC) and ischemic heart disease (IHD). Metho...
Comparar os aspectos anátomo-patológicos da cardiopatia chagásica crônica (CCC) em adolescentes e adultos. De 4.583 autópsias realizadas no Serviço de Anatomia Patológica do Hospital Professor Edgard Santos, entre 1958 e 1986, foram estudados pacientes até os 15 anos de idade, com amastigotas em ...
Objetivo: Avaliar eficácia e tolerância do uso empírico de amiodarona, a longo prazo, em portadores d e Miocardiopatia Chagásica Crônica (MCC) e Taquicardia Ventricular Sustentada (TVS). Casuística e Métodos: Trinta e cinco portadores de MCC e TVS, 18 (51% ) dos quais, refratários a outras drogas...