Results: 6

Evaluation of susceptibility and response in the surface of agents of surface mycoses (Trichophyton mentagrophytes; T. tonsurans) to antifungal drugs of interest in a medical clinic

ABCS health sci; 46 (), 2021
INTRODUCTION: The resistance of fungal species to drugs usually used in clinics is of great interest in the medical field. OBJECTIVE: To evaluate susceptibility and in vitro response of species of Trichophyton spp. to antifungal drugs of interest in clinical medicine. METHODS: 12 samples of clinical isol...

Antifungal and Antioxidant Activities of Vernonia Chalybaea Mart. ex DC. Essential Oil and their Major Constituent β -caryophyllene

Abstract: This article describes the chemical composition of Vernonia chalybaea essential oil, and investigates its antimicrobial, antioxidant and hemolytic activities. The evaluation of the antifungal activity was performed by the broth microdilution method using strains of yeasts and dermatophytic fung...

Minimal inhibitory concentration distributions and epidemiological cutoff values of five antifungal agents against Sporothrix brasiliensis

Mem. Inst. Oswaldo Cruz; 112 (5), 2017
BACKGROUND Sporothrix brasiliensis is the most virulent sporotrichosis agent. This species usually responds to antifungal drugs, but therapeutic failure can occur in some patients. Antifungal susceptibility tests have been performed on this species, but no clinical breakpoints (CBPs) are available. In th...

Efeito da incorporação de agentes antifúngicos na resistência à tração e porosidade de materiais resilientes temporários para base de próteses

Este estudo investigou a resistência à tração (ou limite de resistência à tração- LRT) e a porosidade de reembasadores resilientes temporários modificados por concentrações inibitórias mínimas (CIMs) de agentes antifúngicos para o biofilme Candida albicans (SC5314). Para os testes de LRT, c...

Emprego do cetoconazol em pacientes com doença de Cushing

Com o objetivo de se avaliar a aplicaçäo do efeito antiadrenal do cetoconazol, administramos 600 a 800 mg/dia deste medicamento durante quatro semanas a cinco pacientes com doença de Cushing. Observamos diminuiçäo dos níveis de cortisol plasmático (microng/dl) e urinário (microng/24h) em todos os...

Bases bioquímicas y biofísicas de la acción del ketoconazol sobre epimastigotes de Trypanosoma Cruzi

Se estudió el efecto del ketoconazol como un inhibidor de la reproducción in vitro de los epimastigotes del trypanosoma cruzi, determinando el volumen de restitución del crecimiento de los parásitos por ketoconazol al añadir esteroles exógenos al medio de cultivo, para ello utilizaron reactivos y s...