Besser, Nicolás;
Chacón, Erika;
Iglesias, Andrés;
Álvarez-Lobos, Manuel;
Pavez, Carolina;
Villalón, Constanza;
Urrejola, Gonzalo;
Zúñiga, Álvaro;
Molina, María Elena;
Miguieles, Rodrigo;
Bellolio, Felipe.
BACKGROUND: Treatment for moderate-severe active ulcerative colitis (UC) includes steroids, biologic therapy and total colectomy. Aim: To describe the features of patients with moderate to severe active UC, their hospital evolution and need for colectomy. MATERIAL AND METHODS: Non-concurrent cohort study...
Los anticuerpos anti-TNF-a (tumor necrosis factor alpha) se utilizan para tratar tanto la psoriasis como la enfermedad inflamatoria intestinal (EII). Sin embargo, estos fármacos han sido implicados en la ocurrencia de la psoriasis paradójica en los pacientes sin antecedentes de psorias...
Abstract The purpose of this review was to identify interventions that improve adherence to medications in patients with ulcerative colitis (UC). The literature search was carried out between April and June 2020 in the PubMed/MEDLINE database, with the combination of MeSH terms medication adherence; inte...
Nunes, Vinícius Rodrigues Taranto;
Vidigal, Paula Vieira Teixeira;
Pereira, Márcio Tadeu;
Ladeira, Luís Carlos Duarte;
Caliari, Marcelo Vidigal;
Oliveira, Fabrício Marcus Silva;
Cesar, Aina Liz Alves;
Faraco, André Augusto Gomes;
Barbuto, Rafael Calvão;
Duval-Araujo, Ivana.
ABSTRACT Purpose: The present study aimed at testing a new formulation of mesalazine linked to chondroitin sulfate and its components alone in the treatment of actinic proctitis in rats. Methods: Forty-seven female Wistar rats were submitted to pelvic radiation and divided into eight groups: control A,...
ABSTRACT Purpose To study the Periplaneta americana L. extract Ento-B on the treatment of chronic ulcerative colitis induced by 2,4-dinitrochlorobenzene and acetic acid in rats and to explore its primary mechanism of action. Methods Using 2,4-dinitrochlorobenzene combined with acetic acid to induce chr...
BACKGROUND: Biological therapy and new drugs have revolutionized the treatment of inflammatory bowel disease. Ideally, the choice of medication should be a shared decision with the patient, aiming at greater satisfaction, compliance, and consequently, favorable clinical outcome. OBJECTIVE: This study a...
Administración Oral,
Brasil,
Colitis Ulcerosa/tratamiento farmacológico,
Estudios Transversales,
Fármacos Gastrointestinales/administración & dosificación,
Fármacos Gastrointestinales/uso terapéutico,
Enfermedades Inflamatorias del Intestino/tratamiento farmacológico,
Inyecciones Subcutáneas/estadística & datos numéricos,
Persona de Mediana Edad,
Prioridad del Paciente,
Satisfacción del Paciente,
Encuestas y Cuestionarios,
Terapia Biológica
Vilela, Eduardo Garcia;
Rocha, Henrique Carvalho;
Moraes, Antônio Carlos;
Santana, Genoile Oliveira;
Parente, José Miguel;
Sassaki, Ligia Yukie;
Miszputen, Sender Jenkiel;
Quaresma, Abel Botelho;
Clara, Ana Paula Hamer Sousa;
Jesus, Adélia Carmen Silva de;
Pinto, Arlene dos Santos;
Silva, Bianca Loyo Pona Schiavetti da;
Silva, Bruno César da;
Freire, Caio César Furtado;
Santos, Carlos Henrique Marques dos;
Brito, Carlos;
Teixeira, Ellen Francioni Lima;
Miranda, Eron Fabio;
Zabot, Gilmara Pandolfo;
Duarte, Jozelda Lemos;
Ludvig, Juliano Coelho;
Campos-Lobato, Luiz Felipe de;
Cassol, Ornella Sari;
Souza, Mardem Machado de;
Almeida, Neogélia Pereira de;
Parra, Rogério Serafim;
Lima JÚnior, Sérgio Figueiredo de;
Saad-Hossne, Rogério.
ABSTRACT BACKGROUND: Inflammatory bowel diseases (IBD) are chronic inflammatory affections of recurrent nature whose incidence and prevalence rates have increased, including in Brazil. In long term, they are responsible for structural damage that impacts quality of life, morbidity and mortality of pati...
Abstract Background: Hemophagocytic lymphohistiocytosis (HLH) is considered a medical emergency that should be recognized in patients with fever, splenomegaly, and progressive deterioration of the general condition. Laboratory findings include cytopenia, hypertriglyceridemia, hypofibrinogenemia, and hyp...
Biological therapy dramatically changed the management of Ulcerative Colitis (UC). However, a significant number of these patients fail to respond or have secondary loss of response to this strategy. In this clinical situation, the options include intensification of anti-TNF therapy, the use of a second ...
