In this study, the protectivity of silymarin (SY) against the harmful effects of paclitaxel (PX) on the heart was investigated. PX was administered 2 mg/kg intraperitoneally to the PX group, 100 mg/kg SY wasadministered by gavage to the SY group, and both drugs were administered to the PX + SY group...
SUMMARY: Currently, training in the field of anatomy requires the implementation of learning and knowledge technologies (TAC). Therefore, the objective of this work was to use digital images taken of plastinated canine brains, hearts, and kidneys to create an interactive atlas that facilitates the teachi...
Encéfalo/anatomía & histología,
Corazón/anatomía & histología,
Riñón/anatomía & histología,
Anatomía/educación,
Educación Médica/métodos,
Imagenología Tridimensional,
Siliconas,
Enseñanza,
Aprendizaje,
Atlas,
Modelos Anatómicos,
Plastinación
SUMMARY: The average volumes of normal heart chambers in computed tomography (CT) are used not only as clinical criterions for heart disease diagnosis, but also as references in cardiology. With the development of artificial intelligence (AI), numerous CT data can be analyzed and segmented automatically....
SUMMARY: Etoposide is an effective antimitotic and antineoplastic agent used to treat various human malignancies. In the present study, Etoposide was injected intraperitoneally into the rats at 1 mg/kg/day for 52 days (52 doses). The control animals received physiological saline (0.5 ml) intraperitoneall...
Etopósido/administración & dosificación,
Etopósido/farmacología,
Peso Corporal/efectos de los fármacos,
Tamaño de los Órganos/efectos de los fármacos,
Peroxidación de Lípido,
Antioxidantes/administración & dosificación,
Antioxidantes/farmacología,
Hígado/efectos de los fármacos,
Hígado/ultraestructura,
Riñón/efectos de los fármacos,
Riñón/ultraestructura,
Corazón/efectos de los fármacos,
Miocardio/ultraestructura,
Sistema Enzimático del Citocromo P-450/análisis,
Citocromos b5/análisis,
Ratas Wistar,
Microscopía,
Antineoplásicos Fitogénicos
SUMMARY: Papillary muscles in the left ventricle present multiple anatomic expressions that are relevant for medical fields focusing on the understanding of clinical events involving these structures. Here, the aim was to perform a morphological characterization of the left ventricle papillary muscles in...
Introducción: La disbiosis intestinal o alteración en la composición de la microbiota digestiva está relacionada con la aparición de enfermedades cardiovasculares congénitas y adquiridas que responden a un estado inflamatorio mantenido. Objetivo: Actualizar el conocimiento sobre la relación entre ...
SUMMARY: In response to the threat posed by new variants of SARS-CoV-2 and the urgent need for effective treatments in the absence of vaccines, the aim of this study was to develop a rapid and cost-effective hyperimmune serum (HS) derived from sheep and assess its efficacy. The utilization of a halal-cer...
COVID-19/tratamiento farmacológico,
Inmunoterapia/métodos,
Sueros Inmunes/administración & dosificación,
COVID-19/prevención & control,
COVID-19/inmunología,
SARS-CoV-2/efectos de los fármacos,
Sistema Respiratorio/efectos de los fármacos,
Corazón/efectos de los fármacos,
Vacunas de Productos Inactivados,
Caballos,
Ovinos,
Citometría de Flujo,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Microscopía Electrónica de Transmisión,
Síndrome Respiratorio Agudo Grave/prevención & control,
Insuficiencia Multiorgánica/prevención & control,
Sistema Respiratorio/ultraestructura,
Miocardio/ultraestructura
La miocardiopatía hipertrófica (MCH) es la miocardiopatía hereditaria más frecuente, su principal expresión fenotípica consiste en hipertrofia ventricular izquierda (HVI) en ausencia de condiciones de carga que la justifiquen. Cuando existe una variante genética patogénica se denomina MCH sarcom�...
BACKGROUND Deer heart is a valuable traditional Chinese medicinal material. At present, there is no functional component or symbol component for deer heart, and it is difficult to identify them by physical and chemical methods. In this study, we established deer heart identification method based on mtDNA...
Elkattawy, Hany A;
El-Sayed-Hassan, Ahmed;
Ebrahim-Alsemeh, Amira;
Abdelwahab, Ola A;
Eldesoqui, Mamdouh;
El-Sherbiny, Mohamed;
Ebrahim, Hasnaa Ali;
Nosseir, Nermine Samir;
Veeraraghavan, Vishnu Priya;
Ghazala, Mohamed;
Attia, Mohammed A;
Hadhoud, Shimaa.
SUMMARY: The main cause of mortality and disability globally is myocardial infarction (MI). Isoproterenol (ISO), a β-adrenoceptor agonist, has been used to induce rat myocardial necrosis. Whereas interleukin-37 (IL-37) has anti-inflammatory and cytoprotective properties. The study aimed to investiga...
