LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Environmental enrichment reduces brain excitability in adult rats overnourished during lactation

Alves, Danielle Viana de Souza; Sousa, Mariana Séfora Bezerra; Tavares, Maryane Gabriela; Santos, Luis Gustavo Carvalho dos; Batista-de-Oliveira-Hornsby, Manuella; Amancio-dos-Santos, Angela.

Arq. neuropsiquiatr; 77 (8), 2019

ABSTRACT Objective: This study aimed to analyze whether exposure to environmental enrichment (EE) during the juvenile phase of life interferes with the electrical activity of the adult rat brain. In addition, the present research also investigated whether this putative effect on brain electrical activit...

Conducta Animal/fisiología, Peso Corporal/fisiología, Excitabilidad Cortical/fisiología, Depresión de Propagación Cortical/fisiología, Ambiente, Lactancia/fisiología, Tamaño de los Órganos/fisiología, Hipernutrición/fisiopatología, Distribución Aleatoria, Ratas Wistar, Valores de Referencia, Factores de Tiempo

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Antioxidant extract counteracts the effects of aging on cortical spreading depression and oxidative stress in the brain cortex

Sousa, Mariana Séfora Bezerra; Holanda, Iasmym Melissa Soares de; Monteiro, Heloísa Mirelle Costa; Amâncio-dos-Santos, Ângela.

Acta cir. bras; 33 (6), 2018

Abstract Purpose: To investigate the effects of Murici extract on the brain excitability-dependent phenomenon known as cortical spreading depression (CSD) and on brain oxidative stress. Methods: Adult and aged Wistar rats were supplemented with murici extract (150 mg/kg/day or 300 mg/kg/day) by gavage...

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Brimonidine tartrate effect on retinal spreading depression depends on Müller cells

Oliveira, Vinícius Vanzan Pimentel de; Rodrigues, Marcio Penha Morterá; Alencar, Adroaldo de; Cronemberger, Sebastião; Calixto, Nassim; Dantas, Adalmir Morterá.

Rev. bras. oftalmol; 73 (6), 2014

Objective: Demonstrate the Brimonidine effect over Retinal Spreading Depression (SD). Brimonidine is an alpha-2–adrenergic receptor agonist, used in the management of glaucoma. Alpha2-agonists have been shown to be neuroprotective in various experimental models, however the molecular and cellular t...

Pollos, Depresión de Propagación Cortical/efectos de los fármacos, Depresión de Propagación Cortical/fisiología, Retina/metabolismo, Retina/efectos de los fármacos, Tartrato de Brimonidina/farmacología, Fármacos Neuroprotectores/farmacología, Agonistas de Receptores Adrenérgicos alfa 2/farmacología, Western Blotting, Tomografía de Coherencia Óptica, Glaucoma

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