Introducción. El levetiracetam (LEV) es un antiepiléptico aprobado por el Instituto de Salud Pública de Chile como terapia concomitante en crisis epilépticas en niños mayores de cuatro años. Sin embargo, es ampliamente indicado desde el periodo neonatal, lo que hace necesario evaluar su utilizació...
Epilepsy is the chronic non-communicable disease of the nervous system most prevalent in the world. Valproic acid (VPA) is one of the most used drugs in the treatment of epilepsy but with various side effects. One of the organs that can be affected is the testis, where it has been seen that men treated w...
Muchas enfermedades neurológicas son condiciones crónicas complejas influenciadas
en muchos niveles por cambios en el medio ambiente. El cambio climático (CC) se
refiere a la gama más amplia de cambios locales, regionales y globales en los patrones climáticos promedio, impulsados principalmente, en ...
Objetivo: Reportamos resultados sobre la efectividad,
seguridad y tolerancia del cannabidiol como adyuvante
terapéutico en pacientes pediátricos con encefalopatías
epilépticas del desarrollo (EED) resistentes al tratamiento
farmacológico y no farmacológico tras un seguimiento
promedio de 20 meses. ...
Santos, Andreia Fuentes;
Souza, Marília Moraes Queiroz;
Pauli, Karoline Bach;
da Silva, Gustavo Ratti;
Marques, Midia Wolff;
Auth, Pablo Alvarez;
Bortolucci, Wanessa de Campos;
Gazim, Zilda Cristiani;
Linde, Giani Andrea;
Colauto, Nelson Barros;
Lovato, Evellyn Claudia Wietzikoski;
Lívero, Francislaine Aparecida dos Reis.
Bacopa monnieri(L.) Wettst. (Plantaginaceae), also known as Brahmi, has been used to improve cognitive processes and intellectual functions that are related to the preservation of memory. The objective of this research is to review the ethnobotanical applications, phytochemical composition, toxicity and...
Bacopa/química,
Extractos Vegetales/administración & dosificación,
Enfermedades del Sistema Nervioso Central/tratamiento farmacológico,
Enfermedad de Alzheimer/tratamiento farmacológico,
Enfermedad de Parkinson/tratamiento farmacológico,
Epilepsia/tratamiento farmacológico,
Esquizofrenia/tratamiento farmacológico,
Extractos Vegetales/química,
Sistema Nervioso Central/efectos de los fármacos,
Cognición/efectos de los fármacos,
Saponinas/análisis,
Triterpenos/análisis,
Fitoquímicos
ABSTRACT Background: Epilepsy has neuropsychiatric comorbidities such as depression, bipolar disorder, and anxiety. Drugs that target epilepsy may also be useful for its neuropsychiatric comorbidities. Objective: To investigate the effects of serotonergic modulation on pro-inflammatory cytokines and th...
Anticonvulsivantes/efectos adversos,
Epilepsia/tratamiento farmacológico,
Fluoxetina/efectos adversos,
Interleucina-6,
Pentilenotetrazol/efectos adversos,
Ratas Wistar,
Convulsiones/inducido químicamente,
Convulsiones/tratamiento farmacológico,
Serotonina/efectos adversos,
Sumatriptán/efectos adversos,
Factor de Necrosis Tumoral alfa
ABSTRACT Background: Although epilepsy is primarily known as a cortical disorder, there is growing body of research demonstrating white matter alterations in patients with epilepsy. Objective: To investigate the prevalence of white matter hyperintensities (WMH) and its association with seizure characteri...
There is a close association between sleep and epilepsy, and this literature review aims to raise issues regarding sleep time control, circadian and ultradian rhythms, epilepsy and its
interaction with sleep and circadian rhythm, epilepsy and sleep disorders, and finally epilepsy management and medicatio...
ABSTRACT Background: Epilepsy is highly comorbid with psychiatric disorders and a significant amount of the morbidity related to epilepsy is in fact a result of psychiatric comorbidities. Objective: To investigate the frequency of different psychiatric comorbidities in children with refractory epilepsy...
