SUMMARY: Underage drinking has become a major public concern having a negative impact on the growth and development of the skeleton. Peak bone mass is attained during adolescence hence the aim of the study was to investigate the effect of acute binge alcohol consumption on trabecular morphometry and tens...
Consumo Excesivo de Bebidas Alcohólicas,
Mandíbula/efectos de los fármacos,
Resistencia a la Tracción,
Ratas Sprague-Dawley,
Hueso Esponjoso/efectos de los fármacos,
Factores Sexuales,
Nivel de Alcohol en Sangre,
Fenómenos Biomecánicos,
Densidad Ósea,
Modelos Animales de Enfermedad,
Etanol/toxicidad
SUMMARY: Excessive alcohol consumption adversely affects bone metabolism, thus resulting in reduced bone length, density, and strength. Moreover, these deficits in bone density and strength are likely to increase the risk of fragility fractures and the early onset of osteoporosis. While excessive alcohol...
SUMMARY: Mormodica balsamina is a valuable medicinal plant that is used to treat wounds and inflammation; its leaves are also used as an antibiotic and in the treatment of stomach pain. This study was conducted to determine the anti-ulcer activity of methanolic leaf extract of Mormodica balsamina on etha...
Momordica/química,
Momordica balsamica,
Extractos Vegetales/administración & dosificación,
Hojas de la Planta,
Etanol/toxicidad,
Úlcera Gástrica/tratamiento farmacológico,
Mucosa Gástrica/efectos de los fármacos,
Plantas Medicinales,
Úlcera Gástrica/inducido químicamente,
Extractos Vegetales/química,
Antiulcerosos/administración & dosificación,
Antiulcerosos/química,
Modelos Animales de Enfermedad
The present study was conducted to investigate the underlying mechanisms and effective components of Polygonum hydropiper in ethanol-induced acute gastric mucosal lesions. The ethanol extract was purified on an AB-8 macroporous resin column and eluted with 60% ethanol and was then injected into the HPLC ...
This study evaluated the acute and sub-chronic toxicities of ethanol leaf extract of Dryopteris filix-mas. Acute toxicity and phytochemical tests on ethanol leaf extract were determined. In sub-chronic toxicity test, animals were treated with 62.5, 125, 250 and 500 mg/kg of extract every day for 90 days....
Prolonged alcohol consumption has consequences on the liver, producing necrotic precipitates and fibrosis, on the pancreas, causing the pancreatic acini to atrophy and destroying insulin-producing cells, and on the central nervous system (CNS), causing the gray and white matter in the frontal lobes of th...
Etanol/toxicidad,
Intoxicación Alcohólica/tratamiento farmacológico,
Sistema Nervioso Central/efectos de los fármacos,
Antioxidantes/uso terapéutico,
Hígado/efectos de los fármacos,
Páncreas/efectos de los fármacos,
Estrés Oxidativo,
Etanol/metabolismo,
Sistema Nervioso Central/patología,
Hígado/patología,
Páncreas/patología
Introduction: D-002, a mixture of beeswax alcohols, has been effective in osteoarthritis models and for reducing osteoarthritis symptoms. Unlike the classic anti-inflammatory drugs, D-002 elicits gastroprotective rather than gastrotoxic effects. Lyprinol, used for ameliorating inflammation and arthritic ...
The present work studied the adverse effects of maternal exposure of rats to alcohol during lactation, on the development of their offspring. Histometric evaluation by karyometry and of the palatine epithelium of the sucking was performed. Two groups of animals, one coming from mothers exposed to drinkin...
El consumo materno de etanol durante la lactancia altera la composición de la leche, provoca la aparición de etanol y acetaldehído en la leche y agrava los efectos del etanol en las crías de ratas. De este modo, fueron estudiados los efectos del etanol, administrado a las ratas madres durante la lact...
Etanol/toxicidad,
Nariz/efectos de los fármacos,
Nariz/patología,
Tabique Nasal/efectos de los fármacos,
Tabique Nasal/patología,
Lactancia,
Exposición Materna,
Ratas Wistar,
Cariometría,
Animales Recién Nacidos,
Mucosa Respiratoria/efectos de los fármacos,
Mucosa Respiratoria/patología,
Alcoholismo
