Fernandes, Ana Paula;
Araújo, Leandro Borges;
Colombo, Fábio Antonio;
Ambrosio, Eloá Cristina Passucci;
Silveira, Ana Beatriz Vieira da;
Bergamo, Mariel Tavares Oliveira Prado;
Jorge, Paula Karine;
Machado, Maria Aparecida Andrade Moreira;
Oliveira, Thais Marchini;
Sakai, Vivien Thiemy.
Aim: This study evaluated the effect of different concentrations of transforming growth factor beta 1 (TGF-β1) on stem cells from human exfoliated deciduous teeth (SHED) viability, proliferation, migration and differentiation into odontoblasts. Methods: SHED was treated with different concentrations of ...
SUMMARY: Dystrophin disfunction results in sarcolemma destabilization, leading muscle cell damage by continuous degeneration cycles and limited regeneration. In muscle dystrophy, caused by dystrophin dysfunction, inflammation, necrosis and fibrosis are pathophysiological muscle function loss characterist...
SUMMARY: Laser photobiomodulation (laser PBM) is known to be able to accelerate burn wound healing in the animal model; however little evidence exists on the action of laser PBM on the expression of important proteins in wound healing in the animal model, such as VEGF and TGF-ß1. The aim of this study w...
O desenvolvimento do dente depende de uma série de interações sinalizadoras
recíprocas entre o epitélio oral (EO) e o ectomesênquima derivado da crista
neural, a via WNT com o TGF-β e BMP4 tem sido implicada na tumorigênese. A
via de sinalização tipo Wingless (Wnt) / β-catenina é essencial pa...
Parlar, Ali;
Muñoz-Acevedo, Ammer;
Üçkardeş, Fatih;
Jaimes, Luisauris;
Aneva, Ina;
Morales, Bernardo;
Unis, Amina;
Rodríguez, Maite;
Yumrutas, Onder;
Vinet, Raúl;
Bungau, Simona;
Martínez, José L.
Resveratrol is a phenolic phytoconstituent found in many plants. This molecule has always caught the attention of scientists because of biological potentials such as inhibition of inflammation, oxidative stress and platelet aggregation as well as to prevent/protect against cardiovascular and neurodegen...
Resumen El síndrome de Camurati-Engelmann, también conocido como displasia diafisaria progresiva, es una enfermedad rara, autosómica dominante y con una prevalencia de uno por cada millón de habitantes. Genera mutaciones del factor de crecimiento transformante beta, que participa en la proliferación...
Abstract INTRODUCTION Suckling by schistosomotic mice improves anti-ovalbumin (OA) antibody production, while delayed-type hypersensitivity (DTH) remains unaffected. This property of milk from schistosomotic mice was investigated in IL-12/IL-23-deficient mice (IL-12p40KO). METHODS We compared anti-OA...
The purpose of this study was to investigate the anti-cancer effect of melittin on growth, migration, invasion, and apoptosis of non-small-cell lung cancer (NSCLC) cells. This study also explored the potential anti-cancer mechanism of melittin in NSCLC cells. The results demonstrated that melittin suppre...
Apoptosis,
Factor Apoptótico 1 Activador de Proteasas,
Carcinoma de Pulmón de Células no Pequeñas/tratamiento farmacológico,
Carcinoma de Pulmón de Células no Pequeñas/genética,
Caspasa 3,
Línea Celular Tumoral,
Movimiento Celular,
Regulación hacia Abajo,
Regulación Neoplásica de la Expresión Génica,
Neoplasias Pulmonares/tratamiento farmacológico,
Neoplasias Pulmonares/genética,
Sistema de Señalización de MAP Quinasas,
Meliteno/farmacología,
Invasividad Neoplásica,
Factor de Crecimiento Transformador beta/metabolismo
Abstract Objective This study sought to compare the biocompatibility of a three-dimensional (3D)-printed titanium implant with a conventional machined titanium product, as well as the effect of such implant applied with recombinant human Bone Morphogenetic Protein Type 2 (rhBMP-2) for guided bone regen...
ABSTRACT Purpose To probe the mechanism of mild hypothermia combined with rutin in the treatment of spinal cord injury (SCI). Methods Thirty rats were randomized into the following groups: control, sham, model, mild hypothermia (MH), and mild hypothermia plus rutin (MH+Rutin). We used modified Allen's ...
