Results: 7

Potential antifibrotic effect of blueberry and grape polyphenol extracts in acute and subacute bleomycin-induced lung tissue injury models in mice

Int. j. morphol; 41 (1), 2023
SUMMARY: An experimental morphological and morphometric study of the antifibrotic function of blueberry and grape extracts was carried out on a model of lung injury in mice induced by intraperitoneal administration of bleomycin. During intraperitoneal administration of bleomycin to mice, acute and subacu...

The study of Yangyinyiqi mixture anti bleomycin-induced pulmonary fibrosis on rats by intervening matrix metalloproteinase-9 and tissue inhibitors of matrix metallopreoteinases-1

To investigate effectsof Yangyinyiqi Mixture on pulmonary fibrosis caused by bleomycin. SD ratswere divided randomly into: model group(distilled water,1 mL·0.1 kg-1), dexamethasone acetate group (dexamethasone acetate, the dosage was reduced gradually), low-dose group (Yangyinyiqi Mixture, 11 g·k...

Efecto de la n-acetilcisteina inhalada en el desarrollo de fibrosis pulmonar de ratas intoxicadas con paraquat
Effect of n-acetylcisteine inhaled in the development of pulmonary fibrosis of intoxicated rats with paraquat

Rev. Inst. Nac. Hig; 50 (1-2), 2019
El Paraquat (PQ) es un herbicida de contacto bipiridilico ampliamente utilizado en agricultura. La intoxicación en humanos por este agente ocasiona fibrosis pulmonar. Evaluamos los cambios histológicos pulmonares de ratas intoxicadas con PQ y tratadas con N-aceticisteina (NAC) administrada vía inhalat...

Fibrosis pulmonar aguda asociada a intoxicación por Paraquat: caso clínico

Rev. méd. Chile; 146 (7), 2018
Paraquat, a non-selective bipyridyl pesticide, is one of the leading causes of death from intoxication in many parts of Asia and America. It is the second most sold herbicide worldwide, being widely used in Chile. Its ingestion generates toxicity due to the release of superoxide radicals, mainly affectin...

Efecto inhibitorio de ciclosporina y prednisona sobre la fibrosis pulmonar por bleomicina en la rata
Inhibitory effect of cyclosporin-A and prednisone on bleomycin-induced pulmonary fibrosis in the rat

La administración intratraqueal de bleomicina (BLM) induce una fibrosis pulmonar en la rata detectable al cabo de 14 días. Tanto la ciclosporina-A como la Prednisona (administrada contemporáneamente con la bleomicina y luego diariamente hasta 14 ó 30 días después de BLM) disminuyen en cerca del 50 ...

Efecto de la asociación alopurinol superóxido dismutasa sobre el daño pulmonar experimental inducido por bleomicina
Effect of allopurinol-superoxide dismutase association on experimental pulmonary damage induced by bleomycin

La instilación endotraqueal de bleomicina (BLM) en ratas produce daño pulmonar difuso. A los 3 dias de la administración de BLM se observa edema e inflamación y a los 14 y 30 días fibrosis intersticial. Basándonos en que la liberación de radicales libres del O2 ha sido involucrada en el daño pulm...