ABSTRACT Background: Epilepsy has neuropsychiatric comorbidities such as depression, bipolar disorder, and anxiety. Drugs that target epilepsy may also be useful for its neuropsychiatric comorbidities. Objective: To investigate the effects of serotonergic modulation on pro-inflammatory cytokines and th...
Asociada o no a una enfermedad orgánica, la depresión tiene gran prevalencia en la práctica médica pero es subdiagnosticada. El trastorno del ánimo suele coexistir con variadas quejas somáticas y dolores crónicos, configurando síndromes mixtos con un diagnóstico
diferencial complejo.
En este art...
Chronic antidepressant administration increases neurotrophin levels in the central and peripheral nervous system, leading to an increase of neuronal sprouting, reestablishment of neural networks and neurotransmitter levels. Injured peripheral nerves regenerate at very slow rates. However, the recovery of...
Casos de interacao negativa entre fluoxetina e litio ja foram descritos na literatura, e o mecanismo da interacao parece envolver a acao sinergica no sistema serotosinergico, alem de descricoes de elevacao nos niveis sericos de litio quando da adicao da fluoxetina. Os autores relatam o caso de interacao ...