Results: 4

Endogenous and exogenous serotonin, but not sumatriptan, ameliorate seizures and neuroinflammation in the pentylenetetrazole-induced seizure model in rats

Arq. neuropsiquiatr; 80 (1), 2022
ABSTRACT Background: Epilepsy has neuropsychiatric comorbidities such as depression, bipolar disorder, and anxiety. Drugs that target epilepsy may also be useful for its neuropsychiatric comorbidities. Objective: To investigate the effects of serotonergic modulation on pro-inflammatory cytokines and th...

La depresión: un desafío en la práctica médica general
La depresión: un desafío en la práctica médica general

Asociada o no a una enfermedad orgánica, la depresión tiene gran prevalencia en la práctica médica pero es subdiagnosticada. El trastorno del ánimo suele coexistir con variadas quejas somáticas y dolores crónicos, configurando síndromes mixtos con un diagnóstico diferencial complejo. En este art...

Effects of long-term fluoxetine treatment on adrenergic plasticity in rat vas deferens

Braz. j. pharm. sci; 50 (4), 2014
Chronic antidepressant administration increases neurotrophin levels in the central and peripheral nervous system, leading to an increase of neuronal sprouting, reestablishment of neural networks and neurotransmitter levels. Injured peripheral nerves regenerate at very slow rates. However, the recovery of...

Interacao negativa entre fluoxetina e litio
Negative interaction between fluoxetine and lithium

Casos de interacao negativa entre fluoxetina e litio ja foram descritos na literatura, e o mecanismo da interacao parece envolver a acao sinergica no sistema serotosinergico, alem de descricoes de elevacao nos niveis sericos de litio quando da adicao da fluoxetina. Os autores relatam o caso de interacao ...