Results: 12

Evaluation of the acute toxicity and antidiabetic activity of Coutoubea spicata “nicolau” ethanolic extract and ethyl acetate fraction

In order to understand antidiabetic potential and toxicity, this study aimed to evaluate the acute toxicity and antidiabetic activity of ethanolic extract and ethyl acetate fraction obtained from Coutoubea spicata “nicolau” shoots. Chemical constituents and acute toxicity were investigated. In alloxa...

Estudio biodirigido de metabolitos secundarios con actividad antimicrobiana y aislamiento de D-pinitol de semillas de Leucaena esculenta y L. leucocephala

Phytochemical bio-guided studies are used to find compounds with biological activity. Flavonoids from seeds of Leucaena species have antimicrobial activity in strains of medical interest, therefore, fresh seeds were collected from the town of Tlayacapan, Morelos, Mexico. ...

Phenolic content and antibacterial activity of extracts of Hamelia patens obtained by different extraction methods

Braz. j. microbiol; 49 (3), 2018
Abstract Hamelia patens, is a plant traditionally used to treat a variety of conditions among the Huastec people of Mexico. The objective of this study is to characterize the phenolic content and critically examine the antimicrobial activity of leaf extracts H. patens, obtained by maceration, Soxhlet and...

Statistical tools application on dextranase production from Pochonia chlamydosporia (VC4) and its application on dextran removal from sugarcane juice

An. acad. bras. ciênc; 90 (1), 2018
ABSTRACT The aim of this study was to optimize the dextranase production by fungus Pochonia chlamydosporia (VC4) and evaluate its activity in dextran reduction in sugarcane juice. The effects, over the P. chlamydosporia dextranase production, of different components from the culture medium were analyzed ...

Actiflagelin, a new sperm activator isolated from Walterinnesia aegyptia venom using phenotypic screening

Sperm contains a wealth of cell surface receptors and ion channels that are required for most of its basic functions such as motility and acrosome reaction. Conversely, animal venoms are enriched in bioactive compounds that primarily target those ion channels and cell surface receptors. We hypothesized, ...

Anticariogenic activity of the active fraction from isertia laevis against S. mutans and S. sobrinus: comparison of two extraction methods

Acta odontol. latinoam; 23 (3), 2010
Dental caries is considered a multi-factorial, infectious, chronic, localized, post-eruptive, transmissible disease that leads to the destruction of dental hard tissue. The recognition of Streptococcus mutans as the major bacterial species involved in dental caries has led to the implementation of preven...

Estudo farmacognóstico e farmacológico de Bredemeyera floribunda Willdenow

Bredemeyera floribunda Willdenow, espécie vegetal vulgarmente conhecida como botica inteira, ocorre com freqüência nos campos cerrados do país. A botica inteira, cuja parte empregada são as raízes, é utilizada na medicina popular como expectorante, diurética, em problemas circulatórios e para ba...

Atividade dos inibidores de `alfaï-amilase do triticale parcialmente purificados sobre amilases de Acanthoscelides obtectus e Tenebrio molitor

Inibidores de `alfaï-amilase do triticale (Triticum x secale) foram purificados parcialmente através de fracionamento com sulfato de amônio, filtração em gel sobre Sephadex G-100 e cromatografia em DEAE-Celulose, e foram denominados como 23`B IND. 2ï, 54`B IND. 4ï e 23`C IND. 1ï, conforme varieda...

The effect of pH on the activity of cellulase fractionated between bulk and droplet phases

Aqueous cellulase solutions were vigorously shaked in a separatory funnel, promoting a partition of the enzyme between the droplets formed and the residual bulk solution. The partition coefficient (K ANTPOT. p) was defined as the ratio of protein concentrations in the droplets and in the residual bulk so...