Results: 73

nteraction between FAK/αB-crystalline is important for viability of the glioblastoma cells

Abstract Glioblastoma multiforme is a tumor of the central nervous system. Focal Adhesion Kinase (FAK) and αB-crystalline are two proteins involved in glioblastoma development. In this study, we investigated whether the FAK/αB-crystalline interaction is important for glioblastoma cells, we aimed to inv...

Interação B1R/TLR4 como mecanismo de resposta inflamatória e sua implicação na barreira hematoencefálica em modelo de glioblastoma
B1R/TLR4 interaction as a mechanism of inflammatory response and its implication on the blood-brain barrier in glioblastoma model

A família dos receptores de cininas compreende dois subtipos, sendo o B1R aquele em tem como um de seus agonistas fisiológicos a des-Arg9 -BK (DBK). O receptor B1 tem baixa expressão ou está até mesmo ausente em condições fisiológicas normais, podendo ser induzido por vários estímulos, como o p...

Adesão à quimioterapia antineoplásica oral, apoio social e bem- estar de pacientes com câncer cerebral: estudo correlacional

Objetivos: identificar as percepções sobre o bem-estar, apoio social, intensidade dos sintomas e o seu impacto nas atividades diárias de pacientes com cânceres cerebrais e correlacionar os achados com os níveis de adesão aos quimioterápicos antineoplásicos orais. Método: estudo correlacional e ...

Epidemiological Profile of 96 Intracranial Tumors Treated in a Single Reference Center

Arq. bras. neurocir; 41 (1), 2022
Objectives The present study aims to categorize the prevalence of intracranial tumors surgically treated at the neurosurgery service of Hospital Universitário Evangélico Mackenzie (HUEM) between 2016 and 2018. Material and Methods This survey included patients surgically treated due to primary or metas...

Primary Extra-axial Glioblastoma: Case Report and Literature Review

Arq. bras. neurocir; 40 (4), 2021
Glioblastoma multiforme (GBM) is the most frequent and most aggressive primary brain tumor in adults,mainly located in the cerebral hemispheres. In the literature, few cases of primary GBM have been reported to have radiographic and intraoperative features of extra-axial lesions, leading to a diagnostic ...

Xantoastrocitoma pleomórfico anaplásico y glioblastoma epitelioide: misma entidad o precursor de enfermedad

MedUNAB; 24 (3), 2021
Introducción. El xantoastrocitoma pleomórfico es una lesión glial de bajo grado de malignidad (grado II), puede presentar transformación maligna progresando a xantoastrocitoma pleomórfico anaplásico o glioblastoma multiforme, clasificados en grado III y IV, respectivamente, de acuerdo con la OMS. E...

Glioblastoma multiforme con presentación seudovascular
Glioblastoma multiforme with pseudovascular presentation

Rev. cuba. med; 60 (4), 2021
Introducción: El glioblastoma multiforme es el tumor cerebral primario más frecuente y agresivo en adultos, representa cerca de 25 por ciento de los tumores intracraneales. Las principales manifestaciones clínicas están dadas por cefalea, convulsiones, cambios de conducta y un síndrome focal más de...

Microsurgical Resection of Glioblastoma in a Patient Infected with Covid-19: A Case Report

Arq. bras. neurocir; 40 (3), 2021
The COVID-19 pandemic has affected a large number of patients in all countries, overwhelming healthcare systems worldwide. In this scenario, surgical procedures became restricted, causing unacceptable delays in the treatment of certain pathologies, such as glioblastoma. Regarding this tumor with high mor...

Anesthetic management in neurological disorders: is combined spinal-epidural a suitable option? Case report

Rev. colomb. anestesiol; 49 (3), 2021
Abstract Tuberous sclerosis (TSC) is a rare disease with multi-systemic involvement, predominantly neurological. Little evidence exists about the anesthetic management of patients with this disorder, particularly in pregnant women. This article discusses a case of a patient with TSC admitted to our hospi...